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- Publications
- Influence
Detection of Huntington’s disease decades before diagnosis: the Predict-HD study
- Jane S. Paulsen, D. Langbehn, +13 authors M. Hayden
- Psychology, Medicine
- Journal of Neurology, Neurosurgery, and…
- 20 December 2007
Objective: The objective of the Predict-HD study is to use genetic, neurobiological and refined clinical markers to understand the early progression of Huntington’s disease (HD), prior to the point… Expand
Unified Huntington's disease rating scale: Reliability and consistency
- K. Kieburtz, J. Penney, +47 authors V. Hunt
- Psychology, Medicine
- Movement disorders : official journal of the…
- 1 March 1996
The Unified Huntington's disease Rating Scale (UHDRS) was developed as a clinical rating scale to assess four domains of clinical performance and capacity in HD: motor function, cognitive function,… Expand
A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length
- D. Langbehn, R. Brinkman, D. Falush, Jane S. Paulsen, M. Hayden
- Medicine
- Clinical genetics
- 1 April 2004
Huntington's disease (HD) is a neurodegenerative disorder caused by an unstable CAG repeat. For patients at risk, participating in predictive testing and learning of having CAG expansion, a major… Expand
Huntington disease: natural history, biomarkers and prospects for therapeutics
- C. Ross, E. Aylward, +12 authors S. Tabrizi
- Medicine
- Nature Reviews Neurology
- 1 April 2014
Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is caused by a single genetic mutation and is amenable to predictive genetic testing, with estimation of years to… Expand
Apathy is not depression.
- M. Levy, J. Cummings, +5 authors I. Litvan
- Psychology, Medicine
- The Journal of neuropsychiatry and clinical…
- 1 August 1998
If depression is associated with apathy, then they should be expressed together in different dementia syndromes and should co-occur at varying levels of disease severity. The authors performed a… Expand
Neuropsychiatric aspects of Huntington's disease
- Jane S. Paulsen, R. E. Ready, J. Hamilton, M. Mega, J. Cummings
- Psychology, Medicine
- Journal of neurology, neurosurgery, and…
- 1 September 2001
OBJECTIVE Neuropsychiatric symptoms are common in Huntington's disease and have been considered its presenting manifestation. Research characterising these symptoms in Huntington's disease is… Expand
Is it possible to be schizophrenic yet neuropsychologically normal?
This study identified and characterized a group of schizophrenic patients without neuropsychological (NP) impairment. A comprehensive NP battery was administered to 171 schizophrenic outpatients and… Expand
Psychiatric Symptoms in Huntington’s Disease before Diagnosis: The Predict-HD Study
- K. Duff, Jane S. Paulsen, L. Beglinger, D. Langbehn, Predict-HD Investigators of the Huntington Study Group
- Psychology, Medicine
- Biological Psychiatry
- 15 December 2007
BACKGROUND
Psychiatric disturbances are relatively common in manifest Huntington's disease (HD), but less is known about these symptoms in the earliest phase of the illness.
METHODS
This study… Expand
Neurocognitive signs in prodromal Huntington disease.
- J. Stout, Jane S. Paulsen, +10 authors E. Aylward
- Psychology, Medicine
- Neuropsychology
- 2011
OBJECTIVE
PREDICT-HD is a large-scale international study of people with the Huntington disease (HD) CAG-repeat expansion who are not yet diagnosed with HD. The objective of this study was to… Expand
Dissociations within nondeclarative memory in Huntington's disease.
- B. Knowlton, Larry R. Squire, Jane S. Paulsen, N. Swerdlow, M. Swenson
- Psychology
- 1 October 1996
Patients with Huntington's Disease (HD) were tested on 2 tasks, probabilistic classification learning and artificial grammar learning. Both tasks are performed normally by amnesic patients and are… Expand