Learn More
Many inner ear disorders may be caused by alterations in cochlear blood flow (CBF). However, each measurement technique used to monitor CBF has limitations in examining the relationship between otopathologic states and blood flow. This study investigates laser Doppler flowmetry (LDF) and its fundamental drawback: the unknown relationship of LDF output to(More)
Changes in blood flow to the inner ear have been thought to influence or underlie a number of cochlear diseases, including some forms of noise-induced hearing loss, sudden hearing loss, and Meniere's disease. Recently, important advances have been made in two technologies for the study of cochlear blood flow. The first is in the area of vital microscopic(More)
Internal medicine trainees and faculty recognize the value of effective mentoring to help meet the personal and professional needs of residents. However, the paradigm of the mentor-trainee relationship is seriously threatened by increased clinical, research, and administrative demands on both faculty and housestaff. Moreover, the current criteria for(More)
Ninety-one patients with idiopathic (n = 62) and traumatic (n = 29) facial paralyses were available for evaluation at least 1 year after the onset of paralysis. In nine cases of idiopathic paralysis and in 12 cases of traumatic paralysis, total intratemporal nerve decompression was performed. The remaining patients were treated with steroids alone. All(More)
There is increased emphasis on practicing humanism in medicine but explicit methods for faculty development in humanism are rare. We sought to demonstrate improved faculty teaching and role modeling of humanistic and professional values by participants in a multi-institutional faculty development program as rated by their learners in clinical settings(More)
In a companion paper, we reported that electrical stimulation increased cochlear blood flow (CBF). This response was found to be an increasing function of current intensity and was frequency-selective, with the best response at approximately 500 Hz continuous sinusoidal current. The present investigation seeks to discover the mechanism of this effect.(More)
Postoperative monitoring of microvascular free-tissue transfer is essential to the early identification and correction of vascular compromise. Laser Doppler flowmetry is a noninvasive monitor of capillary bed perfusion. Its current clinical use requires continuous monitoring and trend analysis to detect changes in capillary perfusion. This study(More)
Whereas the anatomy of the vasculature supplying the intratemporal facial nerve is well known, little is known of the dynamics of blood flow within the nerve. The present study was performed to ascertain whether laser Doppler flowmetry (LDF) could detect changes in blood flow within the tympanic segment of the rabbit facial nerve. Compression of the facial(More)
Pentoxifylline, a phosphodiesterase inhibitor and hemorrheologic agent has been found to increase oxygen delivery to ischemic tissue. Intravenous pentoxifylline was administered to normal guinea pigs in order to assess the effect of pentoxifylline on cochlear blood flow and to elucidate its mechanism of action. Intravenous pentoxifylline was found to(More)
A 2-month-old infant developed facial paralysis with a presentation that masqueraded as a possible middle ear tumor. The cause of the paralysis eventually was related to a metabolic consequence of his underlying disorder, cystic fibrosis. To our knowledge, the association of vitamin A imbalance, pseudotumor cerebri, and facial paralysis has not previously(More)