Jane Perryman

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OBJECTIVE To compare the tolerability and efficacy of two doses of i.v. methylprednisolone in patients with secondary-progressive MS. METHODS I.v. methylprednisolone administered in high or low dose every other month for up to 2 years to 108 patients with secondary-progressive MS. RESULTS No significant difference in efficacy with the primary outcome, a(More)
OBJECTIVE To review the rationale, design and baseline data of the Avonex Combination Trial (ACT), an investigator-run study of intramuscular interferon beta-1a (IM IFNbeta-1a) combined with methotrexate (MTX) and/or IV methylprednisolone (IVMP) in relapsing-remitting multiple sclerosis (RRMS) patients with continued disease activity on IM IFNbeta-1a(More)
Introduction: the purpose of school inspection ‘Raising standards, improving lives’ has been Ofsted’s strap line for some time. The strategic plan for 2011-15 specifies this vision in four priorities and indicates a focus on improvement of outcomes for learners of all ages, and a strong focus on underperforming schools. Recent debates in the media, however,(More)
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