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- Publications
- Influence
Cell line‐specific control of recombinant monoclonal antibody production by CHO cells
- P. O'Callaghan, Jane McLeod, +5 authors D. James
- Biology, Medicine
- Biotechnology and bioengineering
- 15 August 2010
In this study we compare the cellular control of recombinant human IgG4 monoclonal antibody (Mab) synthesis in different CHO cell lines. Based on comprehensive empirical analyses of mRNA and… Expand
An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer
- Jane McLeod, P. O'Callaghan, +4 authors D. James
- Biology, Medicine
- Biotechnology and bioengineering
- 1 September 2011
In this study we have combined empirically derived mathematical models of intracellular Mab synthesis to quantitatively compare the degree to which individual cellular processes limit recombinant… Expand
Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial
- D. Hausenloy, Rajesh K Kharbanda, +581 authors Lucy Collier
- Medicine
- The Lancet
- 19 October 2019
Summary Background Remote ischaemic conditioning with transient ischaemia and reperfusion applied to the arm has been shown to reduce myocardial infarct size in patients with ST-elevation myocardial… Expand
Impact of gene vector design on the control of recombinant monoclonal antibody production by chinese hamster ovary cells
- S. Davies, P. O'Callaghan, +7 authors D. James
- Biology, Medicine
- Biotechnology progress
- 1 November 2011
In this study, we systematically compare two vector design strategies for recombinant monoclonal antibody (Mab) synthesis by Chinese hamster ovary (CHO) cells; a dual open reading frame (ORF)… Expand
Engineering Protein Folding and Secretion in Eukaryotic Cell Factories
- Jane McLeod, D. James
- Biology
- 2011
The past two decades have seen a rapid growth in the biopharmaceutical market. Underpinning this is a vast increase in the productivity of eukaryotic expression systems, with cellular engineering… Expand
Quality assessment of online hepatocellular carcinoma patient education materials.
- J. Li, Jane McLeod, P. Ingledew
- Medicine
- 20 May 2020
e24184Background: Hepatocellular carcinoma (HCC) is the fourth-leading cause of cancer-associated death in the world, claiming nearly 800,000 lives each year globally. Concurrently, an increasing n...
Quality Analysis of Online Patient Resources for Hepatocellular Carcinoma.
- Jim Zhang Hao Li, Jane McLeod, P. Ingledew
- Medicine
- Journal of clinical gastroenterology
- 16 December 2020
GOAL
This study aims to evaluate the quality of online hepatocellular carcinoma (primary liver cancer) resources by using a validated tool to determine the strengths and limitations of hepatocellular… Expand
Petitioning the King: The Case of Provincial Printers in Eighteenth-Century France
- H. Hansen, Jane McLeod
- Sociology
- 1 March 2012
This essay studies an argumentative practice in eighteenth-century France by exploring the persuasiveness of some petitions to obtain printer licences. Those who wanted to enter the printing business… Expand
Reflections and best practice recommendations for interdisciplinary working: a case study on the identification of the determinants of addiction from the Addiction and Lifestyles In Contemporary…
- L. Gell, Jane McLeod, J. Holmes, E. Everson-Hock, Petra Meier
- Medicine
- The Lancet
- 19 November 2014
Abstract Background Studies on the determinants of the development of substance use disorders are done across the natural and social sciences. However, research is usually conducted by individual or… Expand
Policing printers and booksellers before and after 1789: a case study in Bordeaux
- Jane McLeod, Renée Girard
- Political Science
- 27 May 2020