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- Peter M. O'Callaghan, Jane McLeod, +5 authors David C James
- Biotechnology and bioengineering
- 2010
In this study we compare the cellular control of recombinant human IgG(4) monoclonal antibody (Mab) synthesis in different CHO cell lines. Based on comprehensive empirical analyses of mRNA and… (More)
- Jane McLeod, Peter M. O'Callaghan, +4 authors David C James
- Biotechnology and bioengineering
- 2011
In this study we have combined empirically derived mathematical models of intracellular Mab synthesis to quantitatively compare the degree to which individual cellular processes limit recombinant… (More)
- Sarah L. Davies, Peter M. O'Callaghan, +7 authors David C James
- Biotechnology progress
- 2011
In this study, we systematically compare two vector design strategies for recombinant monoclonal antibody (Mab) synthesis by Chinese hamster ovary (CHO) cells; a dual open reading frame (ORF)… (More)
- Jane McLeod, David C James
- 2011
The past two decades have seen a rapid growth in the biopharmaceutical market. Underpinning this is a vast increase in the productivity of eukaryotic expression systems, with cellular engineering… (More)
This essay studies an argumentative practice in eighteenth-century France by exploring the persuasiveness of some petitions to obtain printer licences. Those who wanted to enter the printing business… (More)