Jane C Johnson

Learn More
Delta-9-tetrahydrocannabinol (delta-9-THC) prevents cisplatin-induced emesis via cannabinoid CB(1) receptors. Whether central and/or peripheral cannabinoid CB(1) receptors account for the antiemetic action(s) of delta-9-THC remains to be investigated. The 5-hydroxytryptamine (5-HT=serotonin) precursor, 5-hydroxytryptophan (5-HTP), is an indirect 5-HT(More)
The effect of the volatile anesthetic desflurane on spinal and cortical somatosensory evoked potentials (SEPs) was examined in 11 Sprague-Dawley male rats. Platinum recording electrodes were placed stereotactically over the left somatosensory cortex and dorsal midline of the T11-12 spinal cord while the right posterior tibial nerve was stimulated at twice(More)
CONTEXT In the 1940s, osteopathic researchers suggested that paraspinal tissue abnormality was associated with spontaneous muscle activity, but few studies have since re-examined these reports. OBJECTIVE To determine whether abnormal motor activity plays a role in deep paraspinal tissues that appear abnormal to palpation. METHODS Using an observational(More)
This study investigated depression and anxiety among students who were entering medical school prior to the onset of their medical curriculum. Entering students reported financial, day-to-day, academic, and time hassles as concerns. Interestingly, the population characteristics of gender, marital status, and ethnicity impacted the type of self-reported(More)
BACKGROUND Osteopathic manipulative medicine texts and educators advocate a range of approaches for physical assessment and treatment, but little is known about their use by osteopathic physicians in the United States. METHODS A web-based survey using a 5-point Likert scale was developed and e-mailed to 777 practicing osteopathic physician members of the(More)
BACKGROUND The Multicenter Osteopathic Pneumonia Study in the Elderly (MOPSE) is a registered, double-blinded, randomized, controlled trial designed to assess the efficacy of osteopathic manipulative treatment (OMT) as an adjunctive treatment in elderly patients with pneumonia. METHODS 406 subjects aged >/= 50 years hospitalized with pneumonia at 7(More)
BACKGROUND The use of manipulation has long been advocated in the treatment of chronic obstructive pulmonary disease (COPD), but few randomized controlled clinical trials have measured the effect of manipulation on pulmonary function. In addition, the effects of individual manipulative techniques on the pulmonary system are poorly understood. Therefore, the(More)
CONTEXT Although spinal somatic dysfunction diagnosis is taught at all colleges of osteopathic medicine, few objective measures have been used to evaluate student accuracy. OBJECTIVE To assess the palpatory skills of osteopathic medical students in evaluating positional asymmetry in the transverse plane using static block transverse process and lumbar(More)
BACKGROUND The zona incerta (ZI) receives projections from many telencephalic and brainstem structures. On the basis of its connectivity and physiology, this nucleus has been implicated in the control of saccadic eye movements. Because of the complexity of its afferent signals and its simple efferent signal, there must be much local interaction within the(More)
The addition of polytomography considerably increases the sensitivity of pneumoencephalography. The chiasmatic area lends itself particularly well to investigation by polytomoencephalography. In a series of 28 patients, the transverse dimension of the optic chiasm ranged from 4 to 20 mm, with a mean of 18 mm. The posterior portion of the chiasm tended to be(More)