Janardhanan C. Narayanaswamy

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Transcranial direct current stimulation (tDCS) is an upcoming treatment modality for patients with schizophrenia. A series of recent observations have demonstrated improvement in clinical status of schizophrenia patients with tDCS. This review summarizes the research work that has examined the effects of tDCS in schizophrenia patients with respect to(More)
Impaired insight in schizophrenia patients has been linked with prefrontal deficits. In this open-label study, we examined for potential insight facilitation effects of add-on tDCS (with anodal stimulation of left DLPFC and cathodal stimulation over left temporo-parietal junction) in schizophrenia patients (N=21) with persistent auditory hallucinations(More)
BACKGROUND We examined the effect of atomoxetine supplementation in treated-as-usual patients with alcohol, tobacco and other drug dependence (ATOD) and co-morbid externalizing symptoms (ES). METHOD Subjects were selected from a substance dependence treatment-cohort and assessed for: (a) high ES counts, (b) maximum prior period of abstinence, (c) quality(More)
BACKGROUND This study aims to understand the sociodemographic and clinical profile of inhalant abusers seeking treatment from a tertiary care psychiatric hospital in South India. MATERIALS AND METHODS The clinical charts of patients who utilized the psychiatric services of a tertiary care center in India for over 10 years were examined for the study. (More)
The 'cognitive mapping' component of spatial cognition, namely - the allocentric/egocentric function and its relation to symptoms in schizophrenia is relatively unexplored. In this study, we compared schizophrenia patients (N=44) to demographically-matched healthy controls (N=43) using computer-administered visuospatial transformation tasks with egocentric(More)
In this study, the authors report superior temporal gyrus (STG) and Heschl's gyrus (HG) volume deficits in a large sample of medication-naïve patients with schizophrenia (N=55) in comparison with healthy control subjects (N=45) with structural MRI using voxel-based morphometry. Patients had significantly smaller volumes of left HG [X=-41, Y=-22, Z=11;(More)
OBJECTIVE To study relationship between insight and clinical characteristics in subjects with obsessive-compulsive disorder (OCD). METHOD Sample included 545 consecutive patients with a primary diagnosis of DSM-IV OCD who consulted a specialty OCD Clinic at a tertiary psychiatric hospital in India between January 2004 and December 2009. They had been(More)
AIM Gender has been considered as one of the possible factors mediating phenotypic expression of obsessive-compulsive disorder (OCD). We examined gender differences in a large sample of subjects with OCD from India with respect to socio-demographic parameters, symptom characteristics, and comorbidity patterns. METHODS Consecutive patients (n=545) who(More)