Janakiraman Vani

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BACKGROUND Adjuvants enhance or modify an immune response that is made to an antigen. An antagonist of the chemokine CCR4 receptor can display adjuvant-like properties by diminishing the ability of CD4+CD25+ regulatory T cells (Tregs) to down-regulate immune responses. METHODOLOGY Here, we have used protein modelling to create a plausible chemokine(More)
Synthetic CpG containing oligodeoxynucleotide Toll like receptor-9 agonist (CpG DNA) activates innate immunity and can stimulate antigen presentation against numerous intracellular pathogens. It was observed that Salmonella Typhimurium growth can be inhibited by the CpG DNA treatment in the murine dendritic cells. This inhibitory effect was mediated by an(More)
Autoimmunity refers to an inappropriate immune response against self-components of the host that results in pathological conditions. Autoimmune diseases are characterized by an activation of autore-active T and B cells, are associated in some cases with the production of patho-genic autoantibodies against self-molecules , culminating in inflammation and(More)
Dendritic cells (DCs) are professional antigen presenting cells, which play a crucial role both in maintaining immune tolerance and in inducing adaptive immune responses. Therefore, DCs are the most sought in inciting autoimmu-nity and its sustenance to autoimmune diseases. The emerging knowledge of the importance of DCs, DC-derived cytoki-nes, and(More)
The versatile solution to path planning of multi robots for industrial based services are presented in this paper. The authors are motivated to solve the challenges of multi robots path planning issues. The hardware based amenable algorithm for optimal path planning of multi robot with behavioural control is developed. The heuristic approach based leader(More)
In mobile ad hoc networks packets are relayed over multiple hops to reach their destination. Due to the features of open medium, dynamic topology, cooperative algorithms, lack of centralized monitoring and management point mobile ad-hoc networks are much more vulnerable to security attacks when compared to the wired networks. A number of secure routing(More)
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