Janakiraman Vani

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BACKGROUND Adjuvants enhance or modify an immune response that is made to an antigen. An antagonist of the chemokine CCR4 receptor can display adjuvant-like properties by diminishing the ability of CD4+CD25+ regulatory T cells (Tregs) to down-regulate immune responses. METHODOLOGY Here, we have used protein modelling to create a plausible chemokine(More)
Autoimmunity refers to an inappropriate immune response against self-components of the host that results in pathological conditions. Autoimmune diseases are characterized by an activation of autore-active T and B cells, are associated in some cases with the production of patho-genic autoantibodies against self-molecules , culminating in inflammation and(More)
Synthetic CpG containing oligodeoxynucleotide Toll like receptor-9 agonist (CpG DNA) activates innate immunity and can stimulate antigen presentation against numerous intracellular pathogens. It was observed that Salmonella Typhimurium growth can be inhibited by the CpG DNA treatment in the murine dendritic cells. This inhibitory effect was mediated by an(More)
To the Editor—Tuberculosis due to My-cobacterium tuberculosis is 1 of the 3 major killers among infectious diseases. Deciphering the interactions between M. tuberculosis and the innate and adaptive immune compartments of the host is critical for understanding the pathogenesis of tuberculosis and for designing effective im-munotherapeutic interventions. By(More)
The versatile solution to path planning of multi robots for industrial based services are presented in this paper. The authors are motivated to solve the challenges of multi robots path planning issues. The hardware based amenable algorithm for optimal path planning of multi robot with behavioural control is developed. The heuristic approach based leader(More)
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