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  • Charles B. Thompson, Alexandre Cloutier, +6 authors Marek Rola-Pleszczynski
  • Biology, Medicine
  • American journal of respiratory cell and…
  • 2006 (First Publication: 1 December 2006)
  • Because cysteinyl-leukotrienes (cysLTs) are major protagonists in the pathophysiology of human asthma, and because neutrophils are involved in the more severe form of asthma, we studied the potentialContinue Reading
  • Djordje M Grbic, Émilie Degagné, +5 authors Fernand-Pierre Gendron
  • Biology, Medicine
  • Inflammatory bowel diseases
  • 2012 (First Publication: 1 August 2012)
  • BACKGROUND Inflammatory bowel diseases are characterized by the presence of CXCL8 at the site of lesions resulting in neutrophil recruitment and loss of tissue functions. We report that P2Y(6)Continue Reading
  • Rémi Gaudreau, Christian Le Gouill, Marie-Hélène Venne, Jana Stankova, Marek Rola-Pleszczynski
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 30 August 2002)
  • Desensitization of G-protein-coupled receptors may involve phosphorylation of serine and threonine residues. The leukotriene B4 (LTB4) receptor (BLT1) contains 14 intracellular serines andContinue Reading
  • Sister Poulin, C. Thompson, +5 authors Marek Rola-Pleszczynski
  • Medicine, Biology
  • Clinical and experimental allergy : journal of…
  • 2011 (First Publication: 1 February 2011)
  • BACKGROUND Cysteinyl leukotrienes (cysLTs) are suggested to be implicated in the process of airway remodelling in asthma. OBJECTIVE We investigated the potential for cysLTs to modulate vascularContinue Reading
  • Maryse Thivierge, Christian Le Gouill, Michel J Tremblay, Jana Stankova, Marek Rola-Pleszczynski
  • Biology, Medicine
  • Blood
  • 1998 (First Publication: 1 July 1998)
  • The chemokine receptor CCR5 can function as a coreceptor for human immunodeficiency virus-1 (HIV-1) entry into CD4(+) T cells and macrophages, especially during the early stages of HIV-1 infection.Continue Reading
  • Darlaine Pétrin, Sylvie Turcotte, Annie-Kim Gilbert, Marek Rola-Pleszczynski, Jana Stankova
  • Biology, Medicine
  • Cellular signalling
  • 2006 (First Publication: 1 April 2006)
  • The constitutive commitment of neutrophils to apoptosis is a key process for the control and resolution of inflammation and it can be delayed by various inflammatory mediators including leukotrieneContinue Reading