Jana Filipová

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The paper presents basic notions of web mining, radial basis function (RBF) neural networks and -insensitive support vector machine regression ( SVR) for the prediction of a time series for the website of the University of Pardubice. The model includes pre-processing time series, design RBF neural networks and -SVR structures, comparison of the results and(More)
OBJECTIVES Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that are not translated into proteins. They are involved in pathogenesis of many diseases including cancer and have a potential to serve as diagnostic and prognostic markers. We aimed to investigate lncRNA expression profiles in bone marrow plasma cells (BMPCs) of(More)
OBJECTIVE We report a case of the patient who 4 years after bilateral salpingo-oophorectomy had adenocarcinoma of ovary. DESIGN Case report. SETTING Department of Obstetrics and Gynecology, Pardubická krajská nemocnice, a.s., Pardubice. SUBJECT AND METHOD A case report of the patient diagnosed and treated at our department. CONCLUSION The risk of(More)
From the accessible material an attempt was made to estimate the frequency of acute toxic disturbances of liver and its relation to all intoxications together with special regard to the composition of noxious substances on the conditions of this country. From 3700 cases of all acute intoxications or serious attempts of intoxication 54 cases were discovered(More)
Immunoglobulin light chain amyloidosis (ALA) is a plasma cell dyscrasia characterized by deposition of amyloid fibrils in various organs and tissues. The current paper is devoted to clarify if ALA has a unique gene expression profile and to its pathogenetic argumentation. The meta-analysis of ALA patients vs. healthy donors, monoclonal gammopathy of(More)
The Toxicological Information Centre replied in 1988 and 1989 some 5500 inquiries. This number comprised 5-7% concerning treatment of acute intoxications with pesticides. More than half of them concerned children who ingested pesticides. In adults in half of inquiries possible intoxication after ingestion was involved, in half intoxication was a result of(More)