Jana Filipová

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OBJECTIVES Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that are not translated into proteins. They are involved in pathogenesis of many diseases including cancer and have a potential to serve as diagnostic and prognostic markers. We aimed to investigate lncRNA expression profiles in bone marrow plasma cells of newly(More)
The paper presents basic notions of web mining, radial basis function (RBF) neural networks and-insensitive support vector machine regression (-SVR) for the prediction of a time series for the website of the University of Pardubice. The model includes pre-processing time series, design RBF neural networks and-SVR structures, comparison of the results and(More)
Immunoglobulin light chain amyloidosis (ALA) is a plasma cell dyscrasia characterized by deposition of amyloid fibrils in various organs and tissues. The current paper is devoted to clarify if ALA has a unique gene expression profile and to its pathogenetic argumentation. The meta-analysis of ALA patients vs. healthy donors, monoclonal gammopathy of(More)