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Research has demonstrated that dyslexic subjects have language processing problems. More recent evidence indicates that dyslexic subjects also suffer a low-level visual information processing deficit. Little evidence is available to indicate the extent to which dyslexic subjects simultaneously show a visual and language processing dysfunction. In this(More)
PURPOSE The primary purpose of this study was to measure the impact of the 21-gene Recurrence Score® result on systemic treatment recommendations and to perform a prospective health economic analysis in stage I-II, node-negative, oestrogen receptor positive (ER+) breast cancer. METHODS Consenting patients with ER+ node negative invasive breast cancer and(More)
OBJECTIVE To determine whether implementation of a metabolic monitoring training program (MMTP) in an urban community-based setting improved monitoring in children treated with second-generation antipsychotics (SGAs) and changed prescription rates of SGAs to children. METHOD The MMTP was implemented in the Vancouver Coastal Health Child and Youth Mental(More)
Chi-square analyses of new data as well as data previously reported by Myrianthopoulos have shown that grandparents of Tay-Sachs carriers die from proportionally the same causes as grandparents of noncarriers. It is unlikely that there is any advantage to being a Tay-Sachs carrier insofar as resistance to tuberculosis is concerned. Our results are further(More)
Parasuicide is not a single syndrome. Subtypes at present recognized are based largely on clinically derived stereotypes. When considering a series of patients, the clinician is unable to handle more than a few attributes at a time. This paper describes the application of three very different clustering algorithms to a material of 350 treated parasuicide(More)
BACKGROUND The use of antipsychotics, especially second-generation antipsychotics (SGAs), for children with mental health disorders in Canada has increased dramatically over the past five years. These medications have the potential to cause major metabolic and neurological complications with chronic use. OBJECTIVE To synthesize the evidence for specific(More)
OBJECTIVES To review the evidence for efficacy and metabolic effects of atypical antipsychotics (AAPs), and to propose a metabolic monitoring protocol for AAP use in children and adolescents. METHODS A PubMed search was performed to obtain all studies related to efficacy, metabolic side-effects, and monitoring in those less than 18 years of age. RESULTS(More)
Previous studies have noted that a considerable proportion of suicidal behavior is impulsive. The present study aimed to ascertain the degree to which this was so and to consider whether impulsive attempters differed from non-impulsive attempters on variables such as demographic and motivational factors and circumstances that surrounded the occurrence of(More)
OBJECTIVE To compare the rates of obesity, impaired fasting glucose (IFG), and type 2 diabetes between second-generation antipsychotic (SGA)-treated and -naive youth. METHODS A retrospective chart review was conducted for all child and adolescent psychiatry emergency admissions over 2.5 years. Data collected included age, sex, psychiatric diagnosis,(More)