Jan Zacharias

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A first step toward three-dimensional protein structure description is the characterization of secondary structure. The most widely used program for secondary structure assignment remains DSSP, introduced in 1983, with currently more than 400 citations per year. DSSP output is in a one-letter representation, where much of the information on DSSP's internal(More)
We present an alternative to the classical Ramachandran plot (R-plot) to display local protein backbone structure. Instead of the (φ, ψ)-backbone angles relating to the chemical architecture of polypeptides generic helical parameters are used. These are the rotation or twist angle ϑ and the helical rise parameter d. Plots with these parameters provide a(More)
Fine-tuning of a deep convolutional neural network (CNN) is o‰en desired. Œis paper provides an overview of our publicly available py-faster-rcnn-… so‰ware library that can be used to €ne-tune the VGG CNN M 1024 model on custom subsets of the Microso‰ Common Objects in Context (MS COCO) dataset. For example, we improved the procedure so that the user does(More)
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