Jan Valentin Jørgensen

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In a family of 14 brothers and sisters, 3 cases of occlusive disease of the large intracranial vessels (Moya Moya) were found. Each of the three had one or more cerebrovascular attacks and a typical cerebral angiogram. Eight other members of the family had severe headaches. Angiography was carried out in three of these with normal findings.
The effects of thyroid hormones and antithyroid treatment upon lumbar spine bone mineral content (lumbar BMC) were studied in a consecutive series of patients with myxoedema and thyrotoxicosis, respectively. All patients were investigated in the untreated state and 3-monthly during appropriate treatment for 1 year by using dual-photon [153Gd](More)
Pain intensity, and blood glucose and plasma cortisol concentrations were measured following abdominal hysterectomy in 18 patients allocated randomly to receive either i.v. lignocaine 1.5 mg kg-1 plus 2 mg kg-1 h-1, or saline. The administration of lignocaine resulted in plasma concentrations between 1.5 and 2.0 micrograms ml-1 during the 2-h study period.(More)
BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) inhibit platelet function, and use of these drugs has been associated with bleeding events. The objective of this study was to examine whether the requirement for red blood cell transfusion was increased following preoperative use of SSRIs among patients undergoing coronary artery bypass grafting(More)
OBJECTIVES To analyze the frequency of mutations associated with Parkinson's disease (PD) in a general PD population compared to patients with PD selected for deep brain stimulation (DBS) and evaluate the outcome of surgery. MATERIAL AND METHODS A total of 630 consecutive patients with PD were genetically screened, and 60 had DBS surgery, 37 subthalamic(More)
BACKGROUND Extracranial metastases from meningioma are rare, and are reported to occur in less than 1 per 1000. CASE REPORT We report a 54-year-old man, who presented with a parasagittal meningioma with skull erosion and overlying soft tissue invasion. Tumour invading the superior sagittal sinus was not removed, and postoperative radiation was therefore(More)
A prospective randomized study on the effect of doxycycline alone, tinidazole alone and the two antimicrobials in two different combinations as prophylactic antimicrobials on elective colorectal surgery is presented (Table II). The number of patients included in the study was 265. Of the four different treatment groups, the one which consisted of a single(More)
Pellagra secondary to antituberculous chemotherapy can result from isoniazide therapy, as well as from pyrazinamide treatment. Because of the similarity in structural formulas between pyrazinamide, isoniazide, and nicotinamide, the substrate competition is the mechanism most likely involved. The patient was cured by administration of nicotinamide during(More)
Histologic examination of mammary tissue from 39 patients with cyclical mastalgia and 68 with no mastalgia disclosed that fibrocystic disease was not in itself the cause of the cyclical condition. Nor did the study support the traditional concept of a relationship between major dysfunction of the internal genital organs and cyclical mastalgia. Although the(More)