Jan T. Bosiers

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We have built an all-solid-state camera that is directly modulated at the pixel level for frequency-domain fluorescence lifetime imaging microscopy (FLIM) measurements. This novel camera eliminates the need for an image intensifier through the use of an application-specific charge coupled device design in a frequency-domain FLIM system. The first stage of(More)
This paper gives a review of the performance of CCD imagers for use in consumer, professional and scientific applications. An overview of recent developments and the current state-of-the-art are presented. An extensive list of references is included. © 2001 Elsevier Science. All rights reserved Keywords; CCD, imaging PACS: the PACS codes can be found at the(More)
A new-generation full-frame 36x48 mm 2 48Mp CCD image sensor with vertical anti-blooming for professional digital still camera applications is developed by means of the so-called building block concept. The 48Mp devices are formed by stitching 1kx1k building blocks with 6.0 μm pixel pitch in 6x8 (hxv) format. This concept allows us to design four large-area(More)
We developed and implemented a flexible image pre-processing concept to achieve an image sub-system for top-end professional digital still camera applications that ensures the highest possible image quality. It supports high-speed multiple-image acquisition and data processing for very-large resolution images, it reduces the design-in time for the customers(More)
Introduction Though CMOS is taking over from CCD in many application areas, CCDs are still the preferred solution for some very-large (>35mm format) imagers for professional photography and for large field-of-view digital aerial photogrammetry applications. This paper first focuses on some recent developments w.r.t. technology and design, and then presents(More)
MEM-FLIM, a CCD imager for use in advanced Fluorescence Lifetime Imaging Microscopy (FLIM) applications is presented. A demodulation frequency of 80MHz is achieved with 4V clock swing with an optimized pixel design. An optional electron-multiplication CCD register using a single-poly electrode structure is included in the imager. Introduction A FLIM system(More)
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