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BACKGROUND The optimal stenting strategy in coronary artery bifurcation lesions is unknown. In the present study, a strategy of stenting both the main vessel and the side branch (MV+SB) was compared with a strategy of stenting the main vessel only, with optional stenting of the side branch (MV), with sirolimus-eluting stents. METHODS AND RESULTS A total(More)
BACKGROUND It is unknown whether the preferred 1-stent bifurcation stenting approach with stenting of the main vessel (MV) and optional side branch stenting using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies of MV stenting with and without FKBD. METHODS AND RESULTS We randomized 477(More)
Cross-sectional studies suggest that an increased urinary albumin excretion rate is associated with cardiovascular disease, dyslipidemia, and hypertension. The purpose of this study was to analyze prospectively whether the urinary albumin-to -creatinine (A/C) ratio can independently predict ischemic heart disease (IHD) in a population-based cohort. In 1983,(More)
AIMS/HYPOTHESIS Diabetes mellitus is believed to increase susceptibility to infectious diseases. The effects of hyperglycaemia per se on infectious disease risk are unknown and the influence of diabetes on infectious disease outcome is controversial. MATERIALS AND METHODS We studied 10,063 individuals from the Danish general population, who were(More)
AIMS Exenatide, a glucagon-like-peptide-1 analogue, increases myocardial salvage in experimental settings with coronary occlusion and subsequent reperfusion. We evaluated the cardioprotective effect of exenatide at the time of reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary(More)
INTRODUCTION Excessive sympathoadrenal activation in critical illness contributes directly to organ damage, and high concentrations of catecholamines damage the vascular endothelium. This study investigated associations between potential drivers of sympathoadrenal activation, circulating catecholamines and biomarkers of endothelial damage and outcome in ST(More)
A comparative analysis of the information contained in five different classification systems was performed. The system classifying the fractures into five types in relation to the comminution of the calcar femorale or greater trochanter was found to be superior to the others, as it contained the most reliable information about the possibility of obtaining(More)
BACKGROUND Tissue Doppler imaging (TDI) detects left ventricular dysfunction in patients with heart failure and normal ejection fraction, but the prognostic significance of left ventricular dysfunction by TDI in the general population is unknown. METHODS AND RESULTS Within the Copenhagen City Heart Study, a large community-based population study, cardiac(More)
A survey was made of 1592 patients, over the age of 50 years, who had sustained a fracture of the hip. The mean age was found to be 77 years, and 76.9 per cent (1224/1592) of the patients were women. Trochanteric fractures accounted for 52.5 per cent (836/1592) of the cases and these patients had a higher mean age than those with femoral neck fractures. The(More)