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Transgenic APP23 mice were generated to model Alzheimer's disease. The APP23 model develops pathological features, learning deficits, and memory deficits analogous to dementing patients. In this report, transgenic mice exhibited several behavioral disturbances indicating the presence of neuropsychiatric symptoms of dementia. Aiming to verify whether the(More)
In chronic low back pain (CLBP) research, the self-discrepancy model has been applied to explain dysfunctional avoidance and persistence behaviour. The main aim of this study was to evaluate whether specific self-discrepancies in patients with CLBP are associated with the abovementioned types of activity-related behaviour and whether changes in(More)
BACKGROUND Optimal surgical management of digital nerve lesions remains uncertain despite the publication of numerous studies. The purposes of this review were primarily to analyze whether there is a superior surgical technique for digital nerve repair and secondarily to statistically verify the variables to be predictors of sensory recovery. METHODS A(More)
INTRODUCTION AND HYPOTHESIS This study aimed to determine the relationship of recurrent cystocele with avulsion of puborectalis muscle and other risk factors. METHODS In this prospective observational cohort study, 245 women undergoing anterior colporrhaphy were invited for a 2-year follow-up visit consisting of a questionnaire, physical examination, and(More)
OBJECTIVE The aim of the present study is to determine the presence and severity of symptoms of anxiety and depression in patients with oropharyngeal dysphagia who visit the outpatient clinic for dysphagia. METHODS Symptoms of anxiety and depression (affective symptoms) were prospectively assessed in 96 patients using the validated Hospital Anxiety and(More)
INTRODUCTION AND HYPOTHESIS The aim of this study was to compare the number of temporary catheter replacements and urinary tract infections after indwelling catheterization for 2 versus 5 days following an anterior colporrhaphy. METHODS Two hundred forty-six patients were randomly assigned to 2 or 5 days of indwelling catheterization. Outcome measures(More)
Durable protection against complex pathogens is likely to require immunity that comprises both humoral and cellular responses. While heterologous prime-boost regimens based on recombinant, replication-incompetent Adenoviral vectors (AdV) and adjuvanted protein have been able to induce high levels of concomitant humoral and cellular responses, complex(More)
Diet composition may affect blood pressure (BP), but the mechanisms are unclear. The aim of the present study was to compare postprandial BP-related responses to the ingestion of pea protein, milk protein and egg-white protein. In addition, postprandial BP-related responses to the ingestion of maltodextrin were compared with those to the ingestion of(More)
OBJECTIVE To examine the impact of personal attributes (coping and negative affectivity) on the association between cumulative exposure to work stressors and cardiovascular disease (CVD). METHODS 6154 employees from the Maastricht Cohort Study (MCS) were selected who had complete data on the MCS Work Stressor Score (MCS-WSS) at three consecutive time(More)
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