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BACKGROUND On the basis of data indicating that volatile anesthetics induce cardioprotection in cardiac surgery, current guidelines recommend volatile anesthetics for maintenance of general anesthesia during noncardiac surgery in hemodynamic stable patients at risk for perioperative myocardial ischemia. The aim of the current study was to compare increased(More)
Infectious agents are possible stimulators of inflammation in atherogenesis. The aim of this study was to investigate if Chlamydia pneumoniae and Helicobacter pylori were associated with elevated levels of tumor necrosis factor alpha (TNFalpha) and interleukin-6 in coronary heart disease (CHD) patients (n=193) and age- and sex-matched controls (n=193) as(More)
OBJECTIVE To investigate sources of variability in serial echocardiographic recordings in a core laboratory we assessed the impact of repeated echo recordings, repeated video measurements and measurements made by different investigators. PATIENTS, METHODS Two investigators each recorded and analysed two-dimensional echos in 12 individuals (n = 24 in(More)
BACKGROUND Evidence suggests that inflammatory mediators contribute to development and progression of chronic heart failure. We therefore tested the hypothesis that immunomodulation might counteract this pathophysiological mechanism in patients. METHODS We did a double-blind, placebo-controlled study of a device-based non-specific immunomodulation therapy(More)
AIMS To examine differences in measurements of left ventricular dimensions and function, and prognostic value between local investigators and a core laboratory in a multicentre serial echocardiographic study. METHODS AND RESULTS Seven hundred and fifty-six patients with acute myocardial infarction and preserved left ventricular function were examined at(More)
During a baseline cardiovascular survey PR was measured in a strictly standardized way in 1832 men aged 40-59 years, free from coronary heart disease (CHD). Of 1758 men still alive, 1585 underwent an identical follow-up study 7 years later. A total of 1570 were in sinus rhythm. The following findings were made: (1) Baseline and follow-up prevalence of a(More)
AIMS The aim of this study was to obtain normal reference ranges and intra-observer reproducibility for left (L) and right (R) atrial (A) volume indexes (VI, corrected for body surface area) and ejection fractions (EF) with real-time three-dimensional echocardiography. METHODS AND RESULTS One hundred and sixty-six participants, 79 males and 87 females,(More)
UNLABELLED In a population-based study including 35,218 infants born alive during the 15-y period 1982-96, 360 (1%) were diagnosed as having a congenital heart defect (CHD). At a follow-up 3-18 y after birth (median 9.5 y) 154 patients (42.8%) were spontaneously cured; of these, 142 (92.2%) had ventricular septal defects (VSDs). Forty-two patients (11.7%)(More)
Cardiac output determined by Doppler echocardiography was compared with that determined by thermodilution at rest and during dobutamine infusion in 10 patients (group A) and by the Fick method at rest in 11 patients (group B). All patients had angina pectoris without valvular heart disease. Maximum spatial blood velocity and cross sectional aortic area were(More)