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Eccentric sinusoidal rotation with the nose facing out or in leads to gain modulation of the vestibulo-ocular reflex (VOR), which is a result of an interaction between angular and translational VOR. There are conflicting reports with regard to the type of interaction. Combined angular and translational VOR during eccentric sinusoidal rotations over a wide(More)
Estrogens promote adenohypophyseal enlargement and tumor transformation, and thyroid hormones antagonize these effects. Hormone-induced pituitary enlargement may be mediated by alterations in pituitary dopaminergic function. The present study examined the effects of chronic (20 days) administration of estradiol benzoate (EB), triiodothyronine (T3), or EB(More)
Animals demonstrate their ability to represent a geometric configuration of their environment and to use this information for spatial decisions in their response space in many situations. In presented experiment, we examined the ability of rats to interpret a configuration of abstract visual stimuli to make spatial decisions in a real response space. We(More)
VOR gain modulation was systematically investigated in the Rhesus monkey (M. mulatta) during centric and variable eccentric (up to 50 cm) sinusoidal rotation (4 Hz, 0.75 degree) with the nose facing in- or outward to test convergence of otolith and semicircular canal afferences. Earth-stationary lit LED-targets were placed at different distances (12-180 cm)(More)
Recently, we demonstrated that methylene blue partially inhibited estradiol-benzoate-induced anterior pituitary hyperplasia in rats. Since central dopaminergic systems participate in the regulation of estrogen-induced anterior pituitary growth and tumor transformation, this study examined whether a 3-week treatment with methylene blue could affect anterior(More)
We studied the ability of monkeys and humans to orient in one spatial frame ("response frame") according to abstract spatial stimuli presented in another spatial frame ("stimulus frame"). The stimuli were designed as simple maps of the "response space". We studied how the transformations of these stimuli affected the performance. The subjects were trained(More)
We showed previously that macaque monkeys (Macaca mulatta) could orient in real space using abstract visual stimuli presented on a computer screen. They made correct choices according to both spatial stimuli (designed as an abstract representation of a real space) and nonspatial stimuli (pictures lacking any inner configuration information). However, we(More)
Our study investigates whether macaque monkeys (Macaca mulatta) are able to make spatial choices in a real space according to abstract visual stimuli presented on a computer screen. We tested whether there was a difference in the processing of stimuli reflecting the configuration of a response space ("spatial stimuli") and stimuli of simple geometrical(More)