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  • Maarten Fornerod, Jan M van Deursen, +5 authors Gerard C Grosveld
  • Medicine, Biology
  • The EMBO journal
  • 1997 (First Publication: 15 February 1997)
  • The oncogenic nucleoporin CAN/Nup214 is essential in vertebrate cells. Its depletion results in defective nuclear protein import, inhibition of messenger RNA export and cell cycle arrest. We recentlyContinue Reading
  • Jeganathan Ramesh Babu, K. Jeganathan, Darren J Baker, Xiaosheng Wu, Ningling Kang-Decker, Jan M van Deursen
  • Biology, Medicine
  • The Journal of cell biology
  • 2003 (First Publication: 3 February 2003)
  • The WD-repeat proteins Rae1 and Bub3 show extensive sequence homology, indicative of functional similarity. However, previous studies have suggested that Rae1 is involved in the mRNA export pathwayContinue Reading
  • K. Jeganathan, Liviu A. Malureanu, Darren J Baker, Susan C. Abraham, Jan M van Deursen
  • Biology, Medicine
  • The Journal of cell biology
  • 2007 (First Publication: 22 October 2007)
  • The physiological role of the mitotic checkpoint protein Bub1 is unknown. To study this role, we generated a series of mutant mice with a gradient of reduced Bub1 expression using wild-type,Continue Reading
  • Colin E.J. Pritchard, Maarten Fornerod, Lawryn H. Kasper, Jan M van Deursen
  • Biology, Medicine
  • The Journal of cell biology
  • 1999 (First Publication: 19 April 1999)
  • Gle2p is implicated in nuclear export of poly(A)+ RNA and nuclear pore complex (NPC) structure and distribution in Saccharomyces cerevisiae. Gle2p is anchored at the nuclear envelope (NE) via a shortContinue Reading