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  • Nadine Laguette, Nadia Rahm, +10 authors Monsef Benkirane
  • Medicine, Biology
  • Cell host & microbe
  • 2012 (First Publication: 16 February 2012)
  • SAMHD1 has recently been identified as an HIV-1 restriction factor operating in myeloid cells. As a countermeasure, the Vpx accessory protein from HIV-2 and certain lineages of SIV have evolved toExpand
  • Steffen Wildum, Michael Schindler, Jan Münch, Frank Kirchhoff
  • Medicine, Biology
  • Journal of Virology
  • 2006 (First Publication: 15 August 2006)
  • ABSTRACT Human immunodeficiency virus type 1 (HIV-1) utilizes Vpu, Env, and Nef to down-modulate its primary CD4 receptor from the cell surface, and this function seems to be critical for theExpand
  • Wolf‐Georg Forssmann, Yu-Han The, +15 authors Reinhold Ernst Schmidt
  • Medicine, Biology
  • Science Translational Medicine
  • 2010 (First Publication: 22 December 2010)
  • An optimized derivative of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide shows antiviral potency and minimal side effects in a Phase I/II clinical trial. Anchors Away: BlockingExpand