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Open source software such as the operating system Linux has in a few years created much attention as an alternative way to develop and distribute software. Open source is to let anyone have access to the source code, so that they can modify it. Open source could be seen as a movement, where communities of highly skilled programmers collectively develop(More)
In writings on the open source software development model, it is often argued that it is successful as a result of the gift economy that embraces activities in online communities. However, the theoretical foundations for this argument are seldom discussed and empirically tested. Starting with the 'classic' theories of gift giving, we discuss how they need(More)
Recent clinical studies have shown that inorganic arsenic trioxide (As(2)O(3)) at low concentrations induces complete remission with minimal toxicity in patients with refractory acute promyelocytic leukemia (APL). Preclinical studies suggest that As(2)O(3) induces apoptosis and possibly differentiation in APL cells. Like APL cells, neuroblastoma (NB) cells(More)
In this document we discuss the applicability of speech act theory as a theoretical foundation for the design of information technology (IT). We pay special attention to the adaptation speech act theory has undergone when applied in the IT-field. One question we address concerns what happens when we import passive descriptive theories from other disciplines(More)
Existing competence systems are based on a rationalistic view of competence. While these competence systems might work in job-based organizations, we argue that in more dynamic settings, such as in knowledge-based organizations , the interest-informed actions that capture the emergent competencies of tomorrow require different types of information(More)
Information technology (IT) support for managing competence is based on a rationalistic view of competence. While these competence systems might work in rationalistic organizations, we argue that in more dynamic settings, such as in innovative organizations, the interest-informed actions that capture the emergent competencies of tomorrow require different(More)
Social media platforms and services have rapidly grown into an important societal phenomenon, lately also with increased impact on business. The relative novelty of its occurrence in a business context, the lack of well-grounded best practice and the scarcity of research, result in organizational decision-makers having to rely on vendor descriptions and(More)
The mammalian achaete-scute homologue, MASH-1, is crucial for early development of the sympathetic nervous system and is transiently expressed in sympathetic neuroblasts during embryogenesis. Here we report that the human homologue (HASH-1) was expressed in all analyzed cell lines (6/6) derived from the sympathetic nervous system tumor neuroblastoma. The(More)