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The objectives of the paper presented here is the comparison of a geometry-based and voxel-based finite element (FE) method preprocessor of the human femur. The models were experimentally validated by strain gauge measurements (principal stress). The correlation coefficients (r) between the three methods (geometry-based FEM, voxel-based FEM, strain gauge(More)
The development of neural cuff-electrodes requires several in vivo studies and revisions of the electrode design before the electrode is completely adapted to its target nerve. It is therefore favorable to simulate many of the steps involved in this process to reduce costs and animal testing. As the restoration of motor function is one of the most(More)
Rosai-Dorfman disease is a lymphoproliferative disease that rarely involves the central nervous system. A 32-year-old patient with an extensive process involving the petroclival region, cavernous sinuses, suprasellar region, anterior cranial fossa, paranasal sinuses, nasal cavity and spinal cord is reported. Sinus histiocytosis with massive lymphadenopathy(More)
For imaging purposes of the spine, segmented image data provides the basis for a variety of modern clinical applications. However, the anatomical complex structure of the spine as well as the extensive degenerative bony deformations apparent in the clinical situation, generally complicate the application of a fully automated segmentation. To serve the(More)
OBJECT Surgical manipulation of the fifth cranial nerve during its intra- or extracranial course may lead to bradycardia or even asystole as well as arterial hypotension, a phenomenon described as the trigeminocardiac reflex (TCR). The authors studied the impact of this reflex on postoperative auditory function in patients undergoing vestibular schwannoma(More)
Giant cell reparative granuloma (GCRG) is an uncommon non-neoplastic reactive tumor that occurs almost exclusively within the mandible and maxilla and can be locally aggressive. Only sporadic cases involving the skull base have been reported. However, this lesion is probably underappreciated because it might be unrecognized or misdiagnosed. We present a(More)
BACKGROUND Quality of life (QOL) has come into focus after treatment for cerebellopontine angle (CPA) lesions. OBJECTIVE This study compared subjective (tinnitus, vertigo) and objective (hearing loss, facial palsy) results of CPA surgery with patient-perceived impairment of QOL. METHODS A retrospective analysis of a consecutive series of 48 patients(More)
INTRODUCTION A cadaveric study was undertaken to investigate the usefulness and reliability of a microscope based navigation system (NS) for skull base surgery. MATERIAL AND METHODS CT-scans (1 mm slices) were performed in 10 fixed cadaver heads after implantation of fiducials. There upon, various skull base dissections were undertaken:(More)
INTRODUCTION 3-Tesla (T) magnetic resonance imaging (MRI) offers high resolution imaging with improved signal quality. It also allows for improved functional investigations, most prominently with respect to fiber tracts and their relation to pathological lesions. Up to now, patients with adjustable shunt systems were not eligible for high field power(More)
OBJECTIVE Resection of large intraosseous sphenoid wing meningiomas is traditionally associated with significant morbidity. Rapid prototyping techniques have become widely used for treatment planning. Yet, the transfer of a treatment plan into the intraoperative situs strongly depends on the experience of the individual surgeon. CLINICAL PRESENTATION(More)