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Platelet activation leads to secretion of granule contents and to the formation of microvesicles by shedding of membranes from the cell surface. Recently, we have described small internal vesicles inContinue Reading
  • M. J. Metzelaar, P L Wijngaard, Peter J. Peters, Jan J. Sixma, Hendrik K Nieuwenhuis, Hans Clevers
  • Biology, Medicine
  • The Journal of biological chemistry
  • 1991
  • To clone the CD63 antigen, originally described as a blood platelet activation marker, we adapted the expression cloning procedure of Seed and Aruffo (Seed, B., and Aruffo, A. (1987) Proc. Natl.Continue Reading
  • Kjell Steinar Sakariassen, P A Aarts, Philip G. de Groot, Wim P M Houdijk, Jan J. Sixma
  • Chemistry, Medicine
  • The Journal of laboratory and clinical medicine
  • 1983 (First Publication: 1 October 1983)
  • A flat perfusion chamber was developed to study the interaction of blood platelets in flowing blood with cultured human vessel wall cells, their connective tissue matrix, and isolated connectiveContinue Reading