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1973
2018
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- Jan Józef Braszko
- Behavioural brain research
- 2002
In this study we attempted to determine behavioural, including cognitive, consequences of the brain AT(1) (losartan, 2 nmol), AT(2) (PD 123319, 1.5 nmol), and joint AT(1)/AT(2) angiotensin receptors… (More)
- Jan Józef Braszko, Anna Walesiuk, Przemyslaw Wielgat
- Journal of the renin-angiotensin-aldosterone…
- 2006
This study tests the hypothesis that the facilitation of learning and improvement of memory observed after an intracerebroventricular (i.c.v.) injection of angiotensin II (Ang II) is, in fact, caused… (More)
- Luis H Llano López, Fernando Caif, +7 authors Pascual Angel Gargiulo
- Pharmacological reports : PR
- 2012
It has been recognized that the stress-related peptides are involved in anxiety states. Angiotensin II receptor blockade by systemic administration of the AT(1) receptor antagonists has been proposed… (More)
- Jan Józef Braszko
- Neuroscience & Biobehavioral Reviews
- 2010
Angiotensin IV (Ang IV) and des-Phe(6)Ang IV are naturally occurring neuroactive peptides of the renin-angiotensin system (RAS) involved in memory processing. However, the relevant mechanisms are… (More)
- Emil Trofimiuk, Anna Walesiuk, Jan Józef Braszko
- Pharmacological research
- 2005
In this study we tested the hypothesis that St John's wort (Hypericum perforatum) may counteract stress-induced memory impairment. Object recognition test and Morris water maze were used to determine… (More)
- Jan Józef Braszko
- Peptides
- 2004
An important role for angiotensin IV (Ang IV) in the processes of learning and memory has now been well established. We have previously found that intracerebroventricular (ICV) administration of Ang… (More)
- Adam Holownia, Jan Józef Braszko
- Biochemical pharmacology
- 2004
Tamoxifen can exert its effects through the competitive inhibition of estrogen receptors or other mechanisms. HepG2 cells lacking estrogen receptors and engineered to overexpress CYP3A4, the most… (More)
- Jan Józef Braszko
- Clinical and experimental hypertension
- 2005
UNLABELLED
This study explores behavioral effects of angiotensin II (Ang II) and a potent AT(1) receptor inhibitor valsartan ((S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine).… (More)
- Jan Józef Braszko
- European Neuropsychopharmacology
- 2009
In this study effect of L745,870, a selective D(4) dopamine (DA) receptor blocker, on the pro-cognitive action of intracerebroventricularly (icv) injected angiotensin IV (Ang IV) and des-Phe(6)-Ang… (More)
- Adam Holownia, Jan Józef Braszko
- Biochemical pharmacology
- 2004
Acetaminophen hepatotoxicity is mediated by an initial metabolic activation and covalent binding of drug metabolites to liver proteins. Acetaminophen metabolites have been shown to affect rat liver… (More)