Jan Hořejší

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In previous papers, we referred to studies of the influence of antiovarian autoantibodies on menstrual cycle disorders in adolescent girls. We examined autoantibodies against ooplasma, zona pellucida, membrana granulosa, theca folliculi interna, and lutein cells. In infertile women in the IVF/ET program, we studied the positivity of antiovarian antibodies(More)
STUDY OBJECTIVE To estimate various organ-specific autoantibodies and detect other endocrine autoimmune disorders and menstrual cycle characteristics in girls with Type 1 insulin dependent diabetes mellitus (IDDM). DESIGN Prospective cohort study from 1993 to 1998, duration 4.5 years. SETTING Diabetes & Endocrine Clinic of the University Hospital,(More)
Granulosa cell juvenile tumours, defined in 1976 by Scully as a separate unit are found mostly in girls during the first two decades of life. On inspection under an optic microscope they are characterized by the presence of non-differentiated "blastemoid" structures and the formation of solid follicular formations and cysts. In our first case we observed a(More)
The sexual development and behavior of 37 women suffering from the gonadal dysgenesis syndrome were investigated. It was found that their sexual development was significantly retarded compared with a control group of 50 fertile patients of the same age. This retardation was greater in a subgroup of 19 women with the Turner syndrome than in a subgroup of 18(More)
  • J Horejsí
  • Annals of the New York Academy of Sciences
  • 1997
Clitoral hypertrophy is usually seen in congenital malformations, specifically in intersexual stages of hormonal expression. Acquired clitoral hypertrophy is a relatively rare condition, and data in the literature concerning this problem are sparse. Articles usually consist only of case reports. Among the contributing factors in the etiology of acquired(More)
The sexual development and sex life of 12 women with the Küstner-Rokitansky syndrome, in whom the developmental anomaly (vaginal agenesis) was corrected through surgery, were examined through structured interviews and by means of questionnaires. The comparison group was 22 women who had regular menses and a functional sex life. All differences between the(More)
The authors investigated 116 women who took hormonal contraceptives. All women were subjected to detailed clinical and biochemical examinations. In the serum a number of biochemical and immunological tests was made. Special attention was paid to the estimation of prealbumin, alpha-1-antitrypsin, alpha-2-macroglobulin, orosomucoid and ceruloplasmin. In(More)