Learn More
This paper provides a tutorial introduction to reconfi-gurable control and surveys recent advances on this topic. Control reconfiguration is an important method of fault-tolerant control that uses the results of a fault diagnosis component to restructure the control loop and to adapt the controller to the faulty plant. This paper describes recent approaches(More)
Oxidative stress induces apoptosis in liver parenchymal cells. The present study demonstrates that the substitution of fructose for glucose as sole carbon source in the incubation medium reduced apoptosis due to reoxygenation up to 50% in cultured rat hepatocytes. This anti-apoptotic action of fructose cannot be explained by the effects of this sugar on the(More)
(1-->3)-beta-D-Glucans represent highly conserved structural components of cell walls in yeast, fungi, or seaweed. However, it is still unknown how they mediate their effects. The aim of this study was to evaluate both intraperitoneal and oral application of seaweed-derived (1-->3)-beta-D-glucan Phycarine. Phycarine showed significant stimulation of(More)
The cellular defense of Müller cells against oxidative and nitrosative stress was examined after the addition of the nitric oxide donor papanonoate. Glucose concentrations of > or = 550 microM efficiently protected the Müller cells from cell death by maintaining high ATP and glutathione and allowing only a moderate increase of free radicals.(More)
A reconfigurable control approach for continuous-time piecewise affine (PWA) systems subject to actuator and sensor faults is presented. The approach extends the concept of virtual actuators and virtual sensors from linear to PWA systems on the basis of the fault-hiding principle that provides the underlying conceptual idea: the fault is hidden from the(More)
The increase in complexity in process control goes along with an increasing need for complete and guaranteed fault diagnosis. In this contribution, we propose a set-based method for complete fault diagnosis for polynomial systems. It is based on a reformulation of the diagnosis problem as a nonlinear feasibility problem, which is subsequently relaxed into a(More)
— A new approach to the reconfigurable control of piecewise affine (PWA) systems after actuator and sensor faults is presented. The approach extends the concept of virtual actuators and virtual sensors from linear to PWA systems on the basis of the fault-hiding principle. The weak fault-hiding goal is introduced as a relaxation of the asymptotic(More)
This paper presents our multi-year experience in the development of a Functional Modeling Compiler (FMC), a new model-based design tool for the development of multi-disciplinary automotive cyber-physical systems. We show how system-level simulation models suitable for design-space exploration of complex architectures can be synthesized from functional(More)