Jan B. Thomassen

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Alterations of the intracellular ubiquitin–proteasome pathway are found in neurodegenerative and inflammatory disorders of the central nervous system, as well as in its malignancies. Inhibitory substrates of the proteasomes represent promising approaches to control autoimmune inflammations and induction of apoptosis in cancer cells. Extracellular(More)
Weak approximate implicitization is a method for finding an algebraic hypersurface q(x)=0 approximating a parametrically represented manifold p(s) by minimizing the integral int<sub>Omega</sub>(q(p(s)))<sup>2</sup>ds. We show that the properties of the original approach to approximate implicitization, such as the high convergence rates and the approximation(More)
The purpose of the present study was to investigate the impact of the use of peripheral blood progenitor cells (PBPCs) on the induction of autologous graft-versus-host disease (GVHD) in patients with advanced breast cancer. 14 women with stage IIIB and 36 women with stage IV breast cancer received cyclosporine (CsA) 2.5 mg kg–1 i.v. daily, d 0–28, and(More)
Recently a variety of algorithms for the approximation of parametric curves and surfaces by algebraic representations have been developed. We test three of these methods on several test cases, keeping track of time and memory consumption of the implementations and the quality of the approximation. Additionally we discuss some qualitative aspects of the(More)
I consider theories of Dirac fermions with different regularizations, leading to different chiral anomalies. I have investigated the Poincaré invariance properties of these theories. I find that both Lorentz and translational invariance are anomalously violated in general, but that they are respected in a theory that is regularized to give a Wess-Zumino(More)
(1) Mitochondrial ATPase (F1) is influenced by specific nucleotides in its kinetic behavior towards its substrates. In this work, initial hydrolysis rates, as well as continuous reaction progress, were measured by recording proton production (equivalent to triphosphate hydrolysis). (2) After preincubation with ATP, F1 hydrolyzes MgITP partly as if it were(More)
1 Institute of Applied Geometry, Johannes Kepler University, Altenberger Str. 69, 4040 Linz, Austria; www.ag.jku.at, Email: firstname.lastname@jku.at 2 SINTEF ICT, P.O. Box 124 Blindern, N–O314 Oslo, Norway; www.math.sintef.no, Email: [Jan.B.Thomassen|Tor.Dokken]@sintef.no 3 Center of Mathematics for Applications, P.O.Box 1053 Blindern, N–0316 Oslo, Norway;(More)