Jan Åman

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GAD treatment and insulin secretion in recent-onset type 1 diabetes.

Johnny Ludvigsson, Maria Karlsson Faresjö, +13 authors Rosaura Casas
The New England journal of medicine
2008

BACKGROUND The 65-kD isoform of glutamic acid decarboxylase (GAD) is a major autoantigen in patients with type 1 diabetes mellitus. This trial assessed the ability of alum-formulated GAD (GAD-alum)… (More)

Good metabolic control is associated with better quality of life in 2,101 adolescents with type 1 diabetes.

Hilary Hoey, H-J Aanstoot, +22 authors Jan Åman
Diabetes care
2001

OBJECTIVE It is unclear whether the demands of good metabolic control or the consequences of poor control have a greater influence on quality of life (QOL) for adolescents with diabetes. This study… (More)

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.

Johnny Ludvigsson, David M Krisky, +68 authors Samuel Baron
The New England journal of medicine
2012

BACKGROUND The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in… (More)

Physical activity but not energy expenditure is reduced in obese adolescents: a case-control study

Ulf Ekelund, Jan Åman, Agneta Yngve, Cecilia Renman, Klaas Roelof Westerterp, Michael Sjöström
The American journal of clinical nutrition
2002

BACKGROUND The influence of physical activity on body weight in children and adolescents is controversial. OBJECTIVE The objective was to test the hypothesis that the intensity and duration of… (More)

New Definition for the Partial Remission Period in Children and Adolescents With Type 1 Diabetes

Henrik Bindesbøl Mortensen, Philip Hougaard, +9 authors Jan Åman
Diabetes care
2009

OBJECTIVE To find a simple definition of partial remission in type 1 diabetes that reflects both residual beta-cell function and efficacy of insulin treatment. RESEARCH DESIGN AND METHODS A total of… (More)

Physiological hyperglycemia slows gastric emptying in normal subjects and patients with insulin-dependent diabetes mellitus.

Erik Schvarcz, Mats Palmér, Jan Åman, Michael Horowitz, Mats Stridsberg, Christian Berne
Gastroenterology
1997

BACKGROUND & AIMS Marked hyperglycemia slows and hypoglycemia accelerates gastric emptying. The aim of this study was to determine the effect of physiological changes in blood glucose gastric… (More)

Persistent differences among centers over 3 years in glycemic control and hypoglycemia in a study of 3,805 children and adolescents with type 1 diabetes from the Hvidøre Study Group.

Thomas Danne, Henrik Bindesbøl Mortensen, +20 authors Jan Åman
Diabetes care
2001

OBJECTIVE Twenty-one international pediatric diabetes centers from 17 countries investigated the effect of simple feedback about the grand mean HbA(1c) level of all centers and the average value of… (More)

Metformin as additional therapy in adolescents with poorly controlled type 1 diabetes: randomised placebo-controlled trial with aspects on insulin sensitivity

Stefan Särnblad, Marianne Kroon, Jan Åman
European journal of endocrinology
2003

OBJECTIVE Metabolic control often deteriorates during puberty in children with type 1 diabetes. The aim of the present study was to investigate whether addition of metformin for 3 Months improves… (More)

Insulin management and metabolic control of type 1 diabetes mellitus in childhood and adolescence in 18 countries. Hvidøre Study Group on Childhood Diabetes.

Henrik Bindesbøl Mortensen, Kenneth J. Robertson, +21 authors Jan Åman
Diabetic medicine : a journal of the British…
1998

Insulin regimens and metabolic control in children and adolescents with Type 1 diabetes mellitus were evaluated in a cross-sectional, non-population-based investigation, involving 22 paediatric… (More)

Are family factors universally related to metabolic outcomes in adolescents with Type 1 diabetes?

Fergus J Cameron, Timothy C Skinner, +21 authors Søren Eik Skovlund
Diabetic medicine : a journal of the British…
2008

AIMS To assess the importance of family factors in determining metabolic outcomes in adolescents with Type 1 diabetes in 19 countries. METHODS Adolescents with Type 1 diabetes aged 11-18 years,… (More)

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