Jamie J. Coleman

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OBJECTIVE To review the evidence for ethnic differences in susceptibility to adverse drug reactions (ADRs) to cardiovascular drugs. DESIGN Systematic review and meta-analysis. DATA SOURCES We searched Medline and Embase to March 2005. Reference lists of identified articles were hand searched for further relevant articles. REVIEW METHODS Studies were(More)
OBJECTIVES To describe the plans of English NHS hospitals to implement ePrescribing systems. DESIGN AND SETTING Questionnaire-based survey of attendees of the National ePrescribing Forum. PARTICIPANTS A piloted questionnaire was distributed to all NHS and non-NHS hospital-based attendees. The questionnaire enquired about any completed or planned(More)
BACKGROUND ePrescribing systems have significant potential to improve the safety and efficiency of healthcare, but they need to be carefully selected and implemented to maximise benefits. Implementations in English hospitals are in the early stages and there is a lack of standards guiding the procurement, functional specifications, and expected benefits. We(More)
BACKGROUND Clinical decision support (CDS) for electronic prescribing systems (computerized physician order entry) should help prescribers in the safe and rational use of medicines. However, the best ways to alert users to unsafe or irrational prescribing are uncertain. Specifically, CDS systems may generate too many alerts, producing unwelcome distractions(More)
OBJECTIVE To understand the medium-term consequences of implementing commercially procured computerized physician order entry (CPOE) and clinical decision support (CDS) systems in 'early adopter' hospitals. MATERIALS AND METHODS In-depth, qualitative case study in two hospitals using a CPOE or a CDS system for at least 2 years. Both hospitals had(More)
OBJECTIVE To investigate the changes in overdue doses rates over a 4-year period in an National Health Service (NHS) teaching hospital, following the implementation of interventions associated with an electronic prescribing system used within the hospital. DESIGN Retrospective time-series analysis of weekly dose administration data. SETTING University(More)
BACKGROUND Even though electronic prescribing systems are widely advocated as one of the most effective means of improving patient safety, they may also introduce new risks that are not immediately obvious. Through the study of specific incidents related to the processes involved in the administration of medication, we sought to find out if the prescribing(More)
OBJECTIVES There is a pressing need to understand the challenges surrounding procurement of and business case development for hospital electronic prescribing systems, and to identify possible strategies to enhance the efficiency of these processes in order to assist strategic decision making. MATERIALS AND METHODS We organized eight multi-disciplinary(More)
BACKGROUND AND AIM We wished to establish the frequency of unexpected hypoglycemia observed in non diabetic patients outside the intensive care unit and to determine if they have a plausible clinical explanation. METHODS We analysed data for 2010 from three distinct sources to identify non diabetic hypoglycaemic patients: bedside and laboratory blood(More)
BACKGROUND The term multiple drug intolerance syndrome (MDIS) has been used to describe patients who express adverse drug reactions to three or more drugs without a known immunological mechanism. OBJECTIVE To identify patient factors that could increase the risk of MDIS. METHOD Inpatient records over a 5-year period were captured from an electronic(More)