Jamie E. Sly

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Publications11
Citations61
Highly Influential Citations7
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Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies.
  • Jing Shi, Ljubica Krsmanovic, +9 authors Sandra A. Springer
  • Biology, Medicine
  • Environmental and molecular mutagenesis
  • 1 December 2011
    • As part of the Stage 3 of the Pig-a international trial, we evaluated 7,12-dimethylbenz(a)anthracene (DMBA) for induction of Pig-a gene mutation using a 28-day repeat dose study design in… Continue Reading
    Bacterial mutagenicity assays: Vehicle and positive control results from the standard Ames assay, the 6- and 24-well miniaturized plate incorporation assays and the Ames II™ assay.
  • Kamala Pant, Shannon Wilson Bruce, +8 authors Rohan Kulkarni
  • Biology, Medicine
  • Environmental and molecular mutagenesis
  • 1 July 2016
    • Bacterial mutation assays are conducted routinely as part of the safety assessment of new chemicals. The OECD Test Guideline (TG) 471 describes the conduct of the standard agar plate Ames assay,… Continue Reading
    Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate.
  • Kamala Pant, Jamie E. Sly, Shannon Wilson Bruce, Cleo D. Leung, Richard H. C. San
  • Biology, Medicine
  • Mutation research
  • 1 July 2008
    • The Syrian hamster embryo (SHE) cell transformation assay has traditionally been conducted with a feeder layer of X-ray irradiated cells to provide growth support to the target cells seeded in low… Continue Reading
    Syrian Hamster Embryo (SHE) cell transformation assay with and without X-ray irradiation of feeder cells using Di(2-ethylhexyl)phthalate (DEHP) and N-nitroso-N-methylnitroguanidine (MNNG).
  • Kamala Pant, Jamie E. Sly, Shannon Wilson Bruce, Andrew D. Scott, Paul L. Carmichael, Richard H. C. San
  • Biology, Medicine
  • Mutation research
  • 1 April 2010
    • The SHE cell transformation assay has traditionally been conducted with a feeder layer of X-ray irradiated cells to provide growth support to the target cells seeded in low numbers. The need for an… Continue Reading