Jamie Coughlin

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Kinetic parameter estimation at the individual voxel level has the powerful ability to represent both spatial distributions and quantitative physiological parameters of interest. In practice, parametric images are commonly quantified by computing mean values for specified ROIs. Nonetheless, the mean operator vastly oversimplifies the available spatial(More)
In the RA-1000, a random-access discrete analyzer, an inert fluorocarbon fluid is used to prevent interaction and carryover. Production-model instruments were evaluated in two laboratories with respect to determination of glucose, creatinine, total protein, inorganic phosphorus, cholesterol, alkaline phosphatase, lactate dehydrogenase, creatine kinase,(More)
Cypermethrin-piperonyl butoxide formulations (1:1, 1:5, 1:10) were evaluated in a laboratory wind tunnel against colony reared, susceptible adult Culex quinquefasciatus mosquitoes. Scourge (4% resmethrin:12% piperonyl butoxide) was used as the standard for comparison. Based on the LC90 data, the 3 cypermethrin-piperonyl butoxide formulations were 2.6-3.7x(More)
Four percent methoprene pellets applied at a rate of 2.2 kg/ha effectively controlled adult Aedes taeniorhynchus emergence (93%) for over 3 weeks. Efficacy declined to 38% 4 weeks posttreatment. At a rate of 4.5 kg/ha, 95% control was maintained for 34 days with the exception of the 5th week when only 72% control was observed.
Both candidate adulticides, Esbiothrin and Bioresmethrin, exhibited quick knockdown 1-h posttreatment. Esbiothrin elicited the fastest knockdown, but Bioresmethrin was more effective at both 1- and 24-h posttreatment than either Esbiothrin or Scourge against both Aedes taeniorhynchus and Culex quinquefasciatus. Mosquitoes treated with Scourge required more(More)
The caged mosquito bioassay places the test insects in a mesh cage in the path of an insecticidal space spray to investigate the effect of a machine or chemical type on mosquito mortality. The effects of different mesh densities on mosquito confinement and mortality were investigated. In addition, the predominant pathway for exposure of a caged mosquito(More)
Wind tunnel experiments showed that secondary pickup of insecticide residue by mosquitoes in cage bioassays had a significant effect on mortality. Cage bioassays using adult Ochlerotatus taeniorhynchus (Wiedemann) investigated the effect of exposure time to a contaminated surface. Cages were dosed in a wind tunnel using the LC50 for naled (0.124 mg a.i./ml)(More)
Field tests of formulated permethrin (Permanone 30:30) and malathion applied by ground ultra-low volume equipment were conducted using caged, laboratory-reared, adult Ochlerotatus taeniorhynchus. Cages were placed in an open field and also in semi-dense scrub pine. Two doses, a high and a medium dose of each compound, were applied as suggested by the label.(More)
Larval susceptibility tests of Culex nigripalpus populations from various areas of Florida have shown resistance to several organophosphorus insecticides since 1984. Although the degree of resistance is low (2 to 7 times), it can be termed tolerance and appears to be the greatest for fenthion, followed by temephos, naled and malathion. It is suggested that(More)
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