James Y. Paton

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There is poor agreement on definitions of different phenotypes of preschool wheezing disorders. The present Task Force proposes to use the terms episodic (viral) wheeze to describe children who wheeze intermittently and are well between episodes, and multiple-trigger wheeze for children who wheeze both during and outside discrete episodes. Investigations(More)
OBJECTIVE To assess whether a physical activity intervention reduces body mass index in young children. DESIGN Cluster randomised controlled single blinded trial over 12 months. SETTING Thirty six nurseries in Glasgow, Scotland. PARTICIPANTS 545 children in their preschool year, mean age 4.2 years (SD 0.2) at baseline. INTERVENTION Enhanced physical(More)
PURPOSE To test for relationships between objectively measured habitual physical activity and fundamental movement skills in a relatively large and representative sample of preschool children. METHODS Physical activity was measured over 6 d using the Computer Science and Applications (CSA) accelerometer in 394 boys and girls (mean age 4.2, SD 0.5 yr).(More)
Childhood obesity has been attributed to a decline in total energy expenditure (TEE). We measured TEE, physical activity, and sedentary behaviour in a representative sample of young children from Glasgow, UK, at age 3 years (n=78), and we did a follow-up study at age 5 years (n=72). Mean physical activity level (TEE/resting energy expenditure) was 1.56 (SD(More)
Objective methods are being used increasingly for the quantification of the amount of physical activity, intensity of physical activity and amount of sedentary behaviour in children. The accelerometer is currently the objective method of choice. In this review we address the advantages of objective measurement compared with more traditional subjective(More)
BACKGROUND Strategies for the prevention and treatment of childhood obesity require a better understanding of the relation between the pattern of free-living physical activity and total energy expenditure (TEE). OBJECTIVE We assessed the relations between TEE and physical activity level (PAL) during engagement in different intensities of physical(More)
OBJECTIVE To test the ability of accelerometry to quantify sedentary behavior in 3- to 4-year-old children. RESEARCH METHODS AND PROCEDURES We developed a cut-off for accelerometry output (validation study) in 30 healthy 3 to 4 year olds, which provided highest sensitivity and specificity for the detection of sedentary behavior relative to a criterion(More)
OBJECTIVE This study aimed to describe levels of physical activity in a representative sample of preschool children and to quantify tracking of activity over 1 year. RESEARCH METHODS AND PROCEDURES Physical activity (mean accelerometry counts/minute) was assessed over 3 days using the Computer Science and Applications accelerometer in 3- to 4-year-old(More)
BACKGROUND High levels of stress have been shown to predict the onset of asthma in children genetically at risk, and to correlate with higher asthma morbidity. Our study set out to examine whether stressful experiences actually provoke new exacerbations in children who already have asthma. METHODS A group of child patients with verified chronic asthma(More)
BACKGROUND The value of interferon-gamma release assays (IGRA) to diagnose active tuberculosis (TB) in children is not established, but these assays are being widely used for this purpose. The authors examined the sensitivity of commercially available IGRA to diagnose active TB in children in the UK compared with the tuberculin skin test (TST). METHODS(More)