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  • James W. Murrough, Dan V. Iosifescu, +9 authors Sanjay J Mathew
  • Medicine, Psychology
  • The American journal of psychiatry
  • 2013 (First Publication: 1 October 2013)
  • OBJECTIVE Ketamine, a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist, has shown rapid antidepressant effects, but small study groups and inadequate control conditions in prior studies haveExpand
  • James W. Murrough, A. Matamala Pérez, Sarah Pillemer, Jessica Stern, Dan V. Iosifescu
  • Medicine
  • Biological Psychiatry
  • 2013 (First Publication: 15 August 2013)
  • BACKGROUND Ketamine is reported to have rapid antidepressant effects; however, there is limited understanding of the time-course of ketamine effects beyond a single infusion. A previous reportExpand
  • Georgia E Hodes, Madeline L. Pfau, +18 authors Scott J. Russo
  • Psychology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2014 (First Publication: 20 October 2014)
  • Significance Depression and anxiety have been linked to increased inflammation. However, we do not know if inflammatory status predates onset of disease or whether it contributes to depressionExpand
  • Sanjay J Mathew, James W. Murrough, Marije aan het Rot, Katherine A Collins, David L. Reich, Dennis S. Charney
  • Medicine, Psychology
  • The international journal of…
  • 2010 (First Publication: 1 February 2010)
  • The N-methyl-D-aspartate (NMDA) glutamate receptor antagonist ketamine may have rapid, albeit transient, antidepressant properties. This study in patients with treatment-resistant major depressionExpand
  • Antonia S. New, Jin Fan, James W. Murrough, Xun Dao Liu, Dennis S. Charney
  • Medicine, Psychology
  • Biological Psychiatry
  • 2009 (First Publication: 1 October 2009)
  • BACKGROUND Sexual violence is an important public health problem in the United States, with 13% to 26% of women reporting a history of sexual assault. While unfortunately common, there is substantialExpand