James W. Joyner

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A three-dimensional wire-length distribution is derived and applied to determine an optimal n-tier multilevel interconnect architecture for a 0.1 µm ASIC. Ideally, utilization of a three-dimensional architecture consisting of four strata for an interconnect limited layout area leads to a 14 times increase in clock frequency, a 92% reduction in total area,(More)
Total knee replacement is an increasingly popular operation for end stage knee arthritis. In the majority it alleviates pain and improves function. However up to 20% of patients remain dissatisfied, even with well-aligned and secure implants. Restoration of a neutral mechanical axis has traditionally been strived for, to improve both function and implant(More)
21 ; tetramethylrhodamine b-isothiocyanate (TRITC)–phalloidin (Sigma), 50 ng ml 21. The secondary antibodies were fluorescein isothiocyanate (FITC)-conjugated anti-rabbit IgG, 1:200; TRITC–donkey anti-guinea-pig IgG, 1:200; FITC–donkey anti-chicken IgY, 1:100 (all from Jackson ImmunoResearch); FITC–goat anti-mouse IgG1, 1:200 (Southern Biotech); Alexa(More)
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