James Thrall

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PURPOSE To quantify the rates of recommendation for additional imaging (RAI) in a large number of radiology reports of different modalities and to estimate the effects of 11 clinically relevant factors. MATERIALS AND METHODS This HIPAA compliant research was approved by the institutional review board under an expedited protocol for analyzing anonymous(More)
PURPOSE To determine the effect of a computerized radiology order entry system rule that prevented nonclinician support staff from completing orders for outpatient computed tomographic, magnetic resonance imaging, and nuclear medicine examinations that received initial low-yield decision support scores in the order entry system. MATERIALS AND METHODS This(More)
This article presents an evaluation of the criteria used for categorical interpretation of the ventilation-perfusion (V/Q) scans performed in the PIOPED study. In addition, the correlation of percent probability estimates with the actual frequency of pulmonary embolism (PE) is presented. Cases which met the PIOPED criteria for various diagnostic categories(More)
This special report aims to inform the medical community about the many challenges involved in managing radiation exposure in a way that maximizes the benefit-risk ratio. The report discusses the state of current knowledge and key questions in regard to sources of medical imaging radiation exposure, radiation risk estimation, dose reduction strategies, and(More)
The growth in medical imaging over the past 2 decades has yielded unarguable benefits to patients in terms of longer lives of higher quality. This growth reflects new technologies and applications, including high-tech services such as multisection computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET). Some part of(More)
PURPOSE To determine whether an appropriately designed computerized order entry system for radiology can be clinically accepted and influence ordering practices. MATERIALS AND METHODS An intranet-based outpatient ordering and scheduling system was designed and implemented beginning in 2001. Indications used to request imaging have been standardized and(More)
Clinical experience with 99mTc-polyphosphate scintigraphy in more than 200 patients with suspected stress fractures is presented. Stress fractures occur in bone which has been weakened as a result of accelerated physiological change induced by excessive muscular and mechanical activity. Unlike traumatic fractures, they are not accompanied by radiographic(More)
PURPOSE To assess image quality and radiation dose reduction with hybrid iterative reconstruction of pediatric chest and abdominal computed tomographic (CT) data compared with conventional filtered back projection (FBP). MATERIALS AND METHODS A total of 234 patients (median age, 12 years; age range, 6 weeks to 18 years) underwent chest and abdominal CT in(More)
Recognition of the importance of angiogenesis to tumor growth and metastasis has led to efforts to develop new drugs that are targeted to angiogenic vasculature. Clinical trials of these agents are challenging, both because there is no agreed upon method of establishing the correct dosage for drugs whose mechanism of action is not primarily cytotoxic and(More)