James R. Stubbs

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An activity-induced increase in energy expenditure theoretically disturbs energy balance (EB) by creating an acute energy deficit. Compensatory responses could influence the weight loss associated with the energy deficit. Individual variability in compensation for perturbations in EB could partly explain why some individuals fail to lose weight with(More)
This study explored the role of life events in triggering both weight loss and weight gain and assessed whether a number of variables differentiated between these two types of weight change. Members of a slimming club (n = 538) completed an online questionnaire concerning two events, which had caused either weight loss or weight gain. They then described(More)
We measured glucose metabolism in five dogs before and 3 weeks after cardiac denervation; after this time myocardial norepinephrine is depleted. The discharge by the myocardium, of 14CO2 from infused 14C-D-glucose (U), decreased following denervation (P = 0.05). The ratio of 14CO2 to total CO2 production, which measured the proportion of glucose to total(More)
It is unclear whether the rate of weight loss, independent of magnitude, affects whole body protein metabolism and the synthesis and plasma concentrations of specific hepatic secretory proteins. We examined 1) whether lean men losing weight rapidly (starvation) show greater changes in whole body protein kinetics, synthesis, and circulating concentrations of(More)
BACKGROUND Lipid loss in the form of vesicles contributes to the red blood cell (RBC) storage lesion, and this loss of lipid is correlated with changes in membrane protein function. Sensitive spectroscopic techniques were used to measure changes in Band 3 oligomeric state during storage of RBCs, compared to metabolic changes and phospholipid loss. The aim(More)
This survey examined self-reported behaviour changes associated with weight loss and maintenance in a group of 292 members of a commercial weight management organisation (CWMO). Mean (SD) joining weight was 89.0 (20.0) kg, duration of membership was 29.1 (16.2) months and time taken to reach their current weight was 16.3 (13.5) months. Mean (SD) weight(More)
OBJECTIVES Examine the association between components of restrained eating, cognitive performance and weight loss maintenance. METHODS 106 women, all members of a commercial slimming organisation for at least 6 months (mean±SD: 15.7±12.4 months), were studied who, having lost 10.1±9.7 kg of their initial weight, were hoping to sustain their weight loss(More)
BACKGROUND A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin. METHODS Case report. RESULTS Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway(More)