James R. Mead

Learn More
1. Introduction acids and 2-monoacylglycerols for tissue utilization [3,4]. Due to the large size of its substrates, the physiological site Atherosclerosis, the underlying cause of heart attacks, of LPL action is at the luminal surface of blood vessels, to stroke and peripheral vascular disease, is responsible for which the enzyme is attached via highly(More)
Increasing evidence suggests that the cytokine transforming growth factor-beta (TGF-beta) inhibits the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by macrophages has been implicated in the pathogenesis of atherosclerosis by stimulating the uptake of lipoprotein particles. Unfortunately, the action of TGF-beta on the(More)
Increasing evidence suggests that the cytokine transforming growth factor-b (TGF-b) inhibits the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by macrophages has been implicated in the pathogenesis of atherosclerosis by stimulating the uptake of lipoprotein particles. Unfortunately, the action of TGF-b on the expression of(More)
Increasing evidence suggests that the cytokine transforming growth factor-b (TGF-b) inhibits the development of atherosclerosis. The lipoprotein lipase (LPL) enzyme expressed by macrophages has been implicated in the pathogenesis of atherosclerosis by stimulating the uptake of lipoprotein particles. Unfortunately, the action of TGF-b on the expression of(More)
  • 1