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OBJECTIVE We sought cognitive event-related potential (ERP) biomarkers of disease progression and subsequent conversion to dementia in mild cognitive impairment (MCI). BACKGROUND Two ERP components, the P600 and N400, are sensitive to abnormal episodic/declarative memory and semantic processing. When congruous category-exemplars are repeated, smaller(More)
The P3a event-related brain potential (ERP) was elicited using a visual three-stimulus oddball paradigm (target, standard, distracter) in which participants responded only to the target. Discrimination task difficulty between the target and the standard was manipulated by varying the size of the standard stimulus circle relative to a constant target(More)
The objective of this review article is to summarize the published details and media citations for all seven face transplants performed to date to point out deficiencies in those reports so as to provide the basis for examining where the field of face transplantation stands, and to act as a stimulus to enhance the quality of future reports and functional(More)
BACKGROUND Nipple-sparing mastectomy has become an accepted treatment for appropriately selected breast cancers. No reports have correlated patient satisfaction following nipple-sparing mastectomy with objective observer assessments. METHODS From 2001 to 2008, nipple-sparing mastectomy and immediate reconstruction were performed on 141 patients. After(More)
Neural circuits mediating repetition effect for semantically congruous words on functional MRI were investigated in seventeen normal elderly (mean age=70). Participants determined if written words were semantically congruent (50% probability) with spoken statements. Subsequent cued-recall revealed robust explicit memory only for congruous items (83% versus(More)
BACKGROUND This study maps the course of the lesser occipital nerve and its potential compression sites in the posterior scalp. METHODS Twenty sides of 10 fresh cadaveric heads were dissected. Two fixed anatomical landmarks were used: the y axis was the vertical midline in the posterior scalp through the midline of the cervical spine. The x axis was a(More)
INTRODUCTION This study was performed to assess the effects of nerve gap repair with isogenic epineural tubes filled with isogenic bone marrow stromal cells (BMSC) as an alternative to autograft repair. METHODS A total of 24 epineural tubes were transplanted as a conduit to bridge 20 mm nerve gap defects in 2 experimental groups. In group 1, the tube was(More)
BACKGROUND In this study, the authors investigated the potential contribution of environmental factors and testosterone levels on androgenic alopecia in women. METHODS Ninety-eight identical female twins were recruited from 2009 to 2011. Subjects were asked to complete a comprehensive questionnaire, provide a sputum sample for testosterone analysis, and(More)
For the first time, this study analyzes the cost of multiple conventional reconstructions and face transplantation in a single patient. This patient is a 46-year-old female victim of a shotgun blast resulting in loss of multiple functional and aesthetic subunits. For over 5 years, she underwent multiple conventional reconstructions with suboptimal results.(More)
BACKGROUND The purpose of this study was to investigate the potential contribution of environmental factors and testosterone on male alopecia. METHODS Ninety-two identical male twins were recruited from 2009 to 2011. A comprehensive questionnaire was completed followed by the acquisition of sputum samples for testosterone analysis and standardized digital(More)