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PURPOSE Because several polypeptide growth factors are known to influence capillary endothelial cell mitogenesis, the authors investigated the presence of some of these molecules in choroidal neovascular membranes (CNVMs) removed surgically from human subjects with age-related macular degeneration (ARMD). METHODS The authors performed immunoelectron(More)
BACKGROUND AND PURPOSE The aim of our study was to evaluate the causes of retinal arterial occlusive disease in African American patients and to compare these etiologies with those observed in Caucasian patients with retinal ischemic symptoms. METHODS We performed a retrospective analysis of a series of consecutive patients evaluated by both the(More)
PURPOSE To determine whether vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), which have been implicated in the development of retinal and choroidal neovascularization, are present in the retinas and optic nerves of patients with diabetes before proliferative retinopathy appears. METHODS Light microscopic(More)
The clinical features and ophthalmologic findings of 20 patients with syphilitic posterior uveitis seen at the Detroit Medical Center from November 1993 through February 1996 were reviewed. The mean age was 58 years; 8 patients were male and 12 were female; and all patients were black. Three of 9 patients tested were HIV positive. Patients were divided into(More)
Amiodarone has been implicated in the pathogenesis of optic neuropathy in several cases. However, that relationship is unclear, as subjects placed on amiodarone represent a high-risk group for various vasoocclusive accidents. In order to investigate the effect of amiodarone on the optic nerve, we examined histopathologically sections of the retrobulbar(More)
Purpm To dctermux the distribution and nahue of free cells inslde the eye chambers. Methods The cdl uwm were performed on IS n0n-mnsecutive par&n sech(yIs per eye (starned ~10th H.E.) of 10 whole eyes of 5 ycung adult rabbits The right eyes were cut horizontally from pole to pole wi~ereas the I& eyes were equally sectionned sagitally. The completely free(More)
The authors describe the unexpected finding of cicatrization of posterior chamber lens haptics to the pars plana. This was found during removal of a secondary, transscleral sewn-in pseudophakos during a retinal reattachment procedure. Ophthalmic history and intraoperative photography revealed pars plana cicatrization of haptics. Despite removal of(More)
C entral retinal vein occlusion (CRVO) is second only to diabetic retinopathy as a vascular cause of vision loss. 1 Visual morbidity and blindness are most commonly due to macular capillary nonperfusion and persistent macular edema, as well as macular hemorrhage, vitreous hemorrhage, retinal detachment, and neovascular glaucoma. 1,2 As the precipitating(More)
Three patients with myasthenia gravis had transient retraction of the upper eyelids which usually followed prolonged upgaze and which persisted for many seconds. This could result from post-tetanic facilitation, myotonia, or a transient contracture. Retraction of this type is to be distinguished from both the long-standing unilateral retraction associated(More)
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