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We did expressional profiling on 24 paired samples of normal esophageal epithelium, Barrett's metaplasia, and esophageal adenocarcinomas. Matching tissue samples representing the three different histologic types were obtained from each patient undergoing esophagectomy for adenocarcinoma. Our analysis compared the molecular changes accompanying the(More)
Despite recent advances in the understanding of its cell biology, glioma remains highly lethal. Development of effective therapies requires a cost-effective in vitro tumor model that more accurately resembles the in vivo tumor microenvironment as standard two-dimensional (2D) tissue culture conditions do so poorly. Here we report on the use of a(More)
—Statistics of radio frequency interference (RFI) observed in the band 1398–1422 MHz during an airborne campaign in the United States are reported for use in analysis and forecasting of L-band RFI for microwave radiometry. The observations were conducted from September to October 2008, and included approximately 92 h of flight time, of which approximately(More)
The impact of L-band radio frequency interference (RFI) on upcoming L-band microwave radiometry missions (including SMOS, Aquarius, and SMAP) remains an issue of concern. Previous ground-based experiments have provided some information , but these campaigns were conducted in local RFI environments only, and the instruments utilized were usually not capable(More)
A replication-defective adenoviral vector, Ad.Egr-TNF.11D, was engineered by ligating the CArG (CC(A/T)6GG) elements of the Egr-1 gene promoter upstream to a cDNA encoding human tumor necrosis factor-alpha. We report here that Ad.Egr-TNF.11D is activated by the clinically important anticancer agents cisplatin, cyclophosphamide, doxorubicin, 5-fluorouracil,(More)
The intent of this project was to use object storage and its database, which has the ability to add custom extensible metadata to an imaging object being stored within the system, to harness the power of its search capabilities, and to close the technology gap that healthcare faces. This creates a non-disruptive tool that can be used natively by both legacy(More)
In our previous theoretical study, we performed target detection using a plasmonic sensor array incorporating the data-processing technique termed "algorithmic spectrometry". We achieved the reconstruction of a target spectrum by extracting intensity at multiple wavelengths with high resolution from the image data obtained from the plasmonic array. The(More)