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BACKGROUND Vancomycin is a common treatment option for skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Given the increasing prevalence of MRSA, vancomycin is widely used as empirical therapy. In patients with lower-limb infections, antimicrobial penetration is often reduced because of decreased vascular(More)
Cefazolin, a first-generation cephalosporin with activity against methicillin-susceptible Staphylococcus aureus and streptococci, is often used to treat lower limb infections caused by these pathogens. Antimicrobial penetration is often limited in these patients due to compromised vasculature. Therefore, we sought to evaluate the exposure profile of(More)
We present our process and analysis for VAST 2014 Mini Challenge 1 and 2, which integrate an off-the-shelf tool, Jigsaw, rapid web-based visualization prototyping using D3, and analytics-based visualizations using Matlab. 1 MINI CHALLENGE 1 The goals of MC1 1 were to understand the structure of the Protectors of Kronos (POK) organization, the connections of(More)
We present our process and analysis for VAST 2014 Mini Challenge 1 and 2, which integrate an off-the-shelf tool, Jigsaw, rapid web-based visualization prototyping using D3, and analytics-based visualizations using Matlab. 1 MINI CHALLENGE 1 The goals of MC1 1 were to understand the structure of the Protectors of Kronos (POK) organization, the connections of(More)
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