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BACKGROUND Interest in the health effects of particulate matter (PM) has focused on identifying sources of PM, including biomass burning, power plants, and gasoline and diesel emissions that may be associated with adverse health risks. Few epidemiologic studies, however, have included source-apportionment estimates in their examinations of PM health(More)
BACKGROUND An emerging body of evidence suggests that ambient levels of air pollution during pregnancy are associated with preterm birth. METHODS To further investigate these relationships we used vital record data to construct a retrospective cohort of 476,489 births occurring between 1994 and 2004 in 5 central counties of metropolitan Atlanta. Using a(More)
BACKGROUND Despite evidence supporting an association between ambient air pollutants and cardiovascular disease (CVD), the roles of the physicochemical components of particulate matter (PM) and copollutants are not fully understood. This time-series study examined the relation between ambient air pollution and cardiovascular conditions using ambient air(More)
A robust methodology was developed to compute population-weighted daily measures of ambient air pollution for use in time-series studies of acute health effects. Ambient data, including criteria pollutants and four fine particulate matter (PM) components, from monitors located in the 20-county metropolitan Atlanta area over the time period of 1999-2004 were(More)
Relationships between ambient levels of selected air pollutants and pediatric asthma exacerbation in Atlanta were studied retrospectively. As a part of this study, temporal and spatial distributions of ambient ozone concentrations in the 20-county. Atlanta metropolitan area during the summers of 1993, 1994, and 1995 were assessed. A universal kriging(More)
Pediatric emergency room visits for asthma were studied in relation to air quality indices in a spatio-temporal investigation of approximately 130,000 visits (approximately 6,000 for asthma) to the major emergency care centers in Atlanta, Georgia, during the summers of 1993-1995. Generalized estimating equations, logistic regression, and Bayesian models(More)
Associations between ambient air pollution levels during weeks 3-7 of pregnancy and risks of cardiovascular malformations were investigated among the cohort of pregnancies reaching at least 20 weeks' gestation that were conceived during January 1, 1986-March 12, 2003, in Atlanta, Georgia. Surveillance records obtained from the Metropolitan Atlanta(More)
RATIONALE Certain outdoor air pollutants cause asthma exacerbations in children. To advance understanding of these relationships, further characterization of the dose-response and pollutant lag effects are needed, as are investigations of pollutant species beyond the commonly measured criteria pollutants. OBJECTIVES Investigate short-term associations(More)
A modified approach to PM2.5 source apportionment is developed, using source indicative SO2/PM2.5, CO/PM2.5, and NOx/PM2.5 ratios as constraints, in addition to the commonly used particulate-phase source profiles. Additional information from using gas-to-particle ratios assists in reducing collinearity between source profiles, a problem that often limits(More)
Non-occupational inhalation and ingestion exposure to polycyclic aromatic hydrocarbons (PAHs) has been studied in 8 non-smoking volunteers through personal air sampling and urinary biomonitoring. The study period was divided into 4 segments (2 days/segment), including weekdays with regular commute and weekends with limited traffic related exposures; each(More)