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Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation*
- M. Shi, James Movius, +12 authors J. Zhang
- Biology, Medicine
- Molecular & Cellular Proteomics
- 2 January 2015
Finding robust biomarkers for Parkinson disease (PD) is currently hampered by inherent technical limitations associated with imaging or antibody-based protein assays. To circumvent the challenges, we… Expand
Targeted Discovery and Validation of Plasma Biomarkers of Parkinson’s Disease
Despite extensive research, an unmet need remains for protein biomarkers of Parkinson’s disease (PD) in peripheral body fluids, especially blood, which is easily accessible clinically. The discovery… Expand
Proteomic profiling in MPTP monkey model for early Parkinson disease biomarker discovery.
Identification of reliable and robust biomarkers is crucial to enable early diagnosis of Parkinson disease (PD) and monitoring disease progression. While imperfect, the slow, chronic… Expand