James McCorriston

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AIMS To demonstrate expression of immunoglobulin light chain mRNA in diagnostic fine needle aspiration (FNA) cytology specimens using an in situ hybridisation (ISH) technique; and to evaluate ISH in a series of reactive lymphoid proliferations and malignant lymphomas. METHODS Forty diagnostic FNA specimens showing a lymphoid cell population were examined(More)
Geolocated social media data provides a powerful source of information about place and regional human behavior. Because little social media data is geolocation-annotated, inference techniques serve an essential role for increasing the volume of annotated data. One major class of inference approaches has relied on the social network of Twitter, where the(More)
Much work on the demographics of social media platforms such as Twitter has focused on the properties of individuals, such as gender or age. However, because credible detectors for organization accounts do not exist, these and future large-scale studies of human behavior on social media can be contaminated by the presence of accounts belonging to(More)
Exercise plays a central role in many peoples' fitness goals. While prior work has examined how individuals pursue these health and fitness goals on general purpose platforms such as Twitter, the lack of precise activity recording has limited detailed analyses of individual and group behaviors. In this study, we explore a recent social media platform(More)
Immunoglobulin heavy chain (IgH) gene rearrangement analysis was performed on 27 fine needle aspiration (FNA) specimens (13 reactive hyperplasia, 11 B cell non-Hodgkin's lymphoma (B-NHL), one Hodgkin's disease and two suspicious of non-Hodgkin's lymphoma). Satisfactory amplification was achieved in 23/27 cases. A polyclonal pattern was seen in 14 cases (11(More)
A method of freezing cytological material for long term storage, based on a modification of that used in tissue typing for the storage of lymphocytes, was developed. The method entails the centrifugation of the specimen, adding 1 ml AB or fetal calf serum and 1 ml 20% dimethyl sulphoxide aliquoted into 2 ml tubes, and storage at -70 degrees C. Cytological(More)