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- Robin Lester Carhart-Harris, David Erritzoe, +12 authors David J. Nutt
- Proceedings of the National Academy of Sciences…
- 2012
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here… (More)
- Sagnik Bhattacharyya, Paul Dugald Morrison, +17 authors Philip K. McGuire
- Neuropsychopharmacology
- 2010
Δ-9-tetrahydrocannabinol (Δ-9-THC) and Cannabidiol (CBD), the two main ingredients of the Cannabis sativa plant have distinct symptomatic and behavioral effects. We used functional magnetic resonance… (More)
- Thomas A. Gardiner, James M. Stone
- J. Comput. Physics
- 2008
We describe a single step, second-order accurate Godunov scheme for ideal MHD based on combining the piecewise parabolic method (PPM) for performing spatial reconstruction, the corner transport… (More)
- James M. Stone, Paul Dugald Morrison, Lyn S. Pilowsky
- Journal of psychopharmacology
- 2007
The dopamine hypothesis of schizophrenia is the principal explanatory model of antipsychotic drug action. Recent discoveries extend our understanding of the neurochemistry of schizophrenia, with… (More)
- Amir Englund, Paul Dugald Morrison, +11 authors Shitij Kapur
- Journal of psychopharmacology
- 2013
Community-based studies suggest that cannabis products that are high in Δ⁹-tetrahydrocannabinol (THC) but low in cannabidiol (CBD) are particularly hazardous for mental health. Laboratory-based… (More)
- Alice Egerton, S. Carvalho Brugger, +4 authors James M. Stone
- Neuropsychopharmacology
- 2012
Many patients with schizophrenia show a limited symptomatic response to treatment with dopaminergic antipsychotics. This may reflect the additional involvement of non-dopaminergic neurochemical… (More)
A new code for astrophysical magnetohydrodynamics (MHD) is described. The code has been designed to be easily extensible for use with static and adaptive mesh refinement. It combines higher-order… (More)
- James M. Stone, Fern Day, +6 authors Philip K. McGuire
- Biological psychiatry
- 2009
BACKGROUND
The glutamate model of schizophrenia proposes that altered glutamatergic neurotransmission is fundamental to the development of the disorder. In addition, its potential to mediate… (More)
In this, the second of a series of three papers, we continue a detailed description of ZEUS-2D, a numerical code for the simulation of uid dynamical ows in astrophysics including a self-consistent… (More)