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Concept maps are an effective way of representing a person's understanding of a domain of knowledge. Technology can further help by making it easy to construct and modify that representation, to manage large representations for complex domains, and to allow groups of people to share in the construction of the concept maps. CmapTools is a software(More)
In this paper, we describe our initial implementation of the KAoS policy and domain services. While initially oriented to the dynamic and complex requirements of software agent applications, the services are also being adapted to general-purpose grid computing and web services environments as well. The KAoS services rely on a DAML description-logic-based(More)
To increase the assurance with which agents can be deployed in operational settings, we have been developing the KAoS policy and domain services. In conjunction with Nomads strong mobility and safe execution features, KAoS services and tools allow for the specification, management, conflict resolution, and enforcement of DAML-based policies within the(More)
Information visualization has been a research topic for many years, leading to a mature field where guidelines and practices are well established. Knowledge visualization, in contrast, is a relatively new area of research that has received more attention recently due to the interest from the business community in Knowledge Management. In this paper we(More)
The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection. As the gene is highly conserved in the mycobacteria, we deleted the Rv3574 orthologue in Mycobacterium smegmatis (MSMEG_6042) and used real-time quantitative(More)
Mycobacterium tuberculosis is able to use a variety of carbon sources in vivo and current knowledge suggests that cholesterol is used as a carbon source during infection. The catabolized cholesterol is used both as an energy source (ATP generation) and as a source of precursor molecules for the synthesis of complex methyl-branched fatty acids. In previous(More)
Theorists and practitioners propose collaborative learning as a recommended methodology within constructivist environments. Concept mapping in particular has been shown to be an effective tool to support collaboration among students. However, seldom are teachers and students provided with the appropriate communication and collaboration tools, many of which(More)
The KAoS policy management framework pioneered the use of semantically-rich ontological representation and reasoning to specify, analyze, deconflict, and enforce policies [9, 10]. The framework has continued to evolve over the last five years, inspired by both technological advances and the practical needs of its varied applications. In this paper, we(More)
The study of visual transduction has given invaluable insight into the mechanisms of signal transduction by heptahelical receptors that act via guanine nucleotide binding proteins (G-proteins). However, the cyclic-GMP second messenger system seen in vertebrate photoreceptor cells is not widely used in other cell types. In contrast, the retina of higher(More)