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  • Jonathan David Roth, Barbara L. Roland, +6 authors Alain D. Baron
  • Medicine, Chemistry
  • Proceedings of the National Academy of Sciences
  • 2008 (First Publication: 20 May 2008)
  • Body weight is regulated by complex neurohormonal interactions between endocrine signals of long-term adiposity (e.g., leptin, a hypothalamic signal) and short-term satiety (e.g., amylin, a hindbrainExpand
  • James L Trevaskis, Peter S. Griffin, +7 authors Jonathan David Roth
  • Biology, Medicine
  • American journal of physiology. Gastrointestinal…
  • 2012 (First Publication: 15 April 2012)
  • These preclinical studies aimed to 1) increase our understanding the dietary induction of nonalcoholic steatohepatitis (NASH), and, 2) further explore the utility and mechanisms of glucagon-likeExpand
  • Gregory M. Sutton, James L Trevaskis, +5 authors Andrew A Butler
  • Biology, Medicine
  • Endocrinology
  • 2006 (First Publication: 1 May 2006)
  • Loss of brain melanocortin receptors (Mc3rKO and Mc4rKO) causes increased adiposity and exacerbates diet-induced obesity (DIO). Little is known about how Mc3r or Mc4r genotype, diet, and obesityExpand
  • Christine M. Mack, Christopher J. Soares, +18 authors David G. Parkes
  • Medicine
  • International Journal of Obesity
  • 2010 (First Publication: 1 February 2010)
  • Objective:The current set of studies describe the in vivo metabolic actions of the novel amylin-mimetic peptide davalintide (AC2307) in rodents and compares these effects with those of the nativeExpand