James L Griffith

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Abdominal pain physiology may be better understood studying electrophysiology, histology, and symptom scores in patients with the symptoms of gastroparesis (Gp) treated with gastric electrical stimulation (GES). Ninety-five Gp patients' symptoms were recorded at baseline and during temporary and permanent GES. Gastric-emptying times and cutaneous, mucosal,(More)
Vitiligo is an acquired skin disorder characterized by the destruction of melanocytes resulting in achromic macules and patches involving the affected skin. Multiple methods of treatments have emerged to manage vitiligo, including medical and surgical techniques. Among the surgical techniques described in the management of vitiligo are minipunch grafting,(More)
BACKGROUND/PURPOSE Ultraviolet A1 (UVA1) phototherapy has been used for over 15 years in the United States, primarily for the treatment of localized sclerosis and various sclerosing disorders. The objective was to describe use of UVA1 for dermatoses beyond localized sclerosis at two academic institutions. METHODS Data from 83 patients treated with low-(More)
DEAR EDITOR, Since its debut in 1992, melanocyte–keratinocyte transplant procedure (MKTP) or a noncultured epidermal suspension technique has proven to be a safe, effective and welltolerated therapeutic option for the repigmentation of stable vitiligo recalcitrant to medical treatment and phototherapy. Despite being an effective, widely adopted(More)
BACKGROUND Primary closure of the perineum at the time of abdominoperineal resection (APR) is seldom successful. Several factors are known to adversely affect healing, including neoadjuvant chemoradiation, tension, contamination, and fluid collection. This study evaluates a 2-team approach for resection and routine perineal closure in a single stage. (More)
Hidradenitis suppurativa (HS) is a chronic inflammatory disease that commonly develops painful, deep dermal abscesses and chronic, draining sinus tracts. Classically, pharmacologic and surgical therapies have been effective for reducing lesion activity and inflammation, but provide only modest success in the prevention of future recurrences and disease(More)
Vitiligo is a disorder characterized by the development of depigmented macules and patches. Narrowband ultraviolet B phototherapy is a standard of care treatment and is used both as monotherapy and in combination with other treatment modalities to induce repigmentation. Although phototherapy is safe and effective, its use is limited due to the significant(More)
altering its function. It can only be cured by removal of the diseased areas. Medical treatment is palliative and consists of change of environment to a more congenial climate, and control of respiratory infections by physiotherapy and antibiotics when necessary. Once established the condition tends to get worse with repeated infections, the result of "(More)