James L. Carr

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In 1965 a massive growth of Ceratophyllum demersum caused the shut-down of one power station (Ohakuri) on the Waikato River. As a result a study was commenced of the biology of the weeds in the Waikato hydro-electric lakes. There are four major exotic weeds, Ceratophyllum, Lagarosiphon major, Egeria densa and Elodea canadensis, all of which form extensive(More)
Catalytic enantioselective allylic substitution (EAS) reactions are of prominent utility in chemical synthesis. Such transformations generate a stereogenic center adjacent to an alkene, which can be further functionalized to afford a range of other enantiomerically enriched molecules. Despite noteworthy advances, several issues remain unresolved in this(More)
A set of protocols for catalytic enantioselective allylic substitution (EAS) reactions that allow for additions of alkenyl units to readily accessible allylic electrophiles is disclosed. Transformations afford 1,4-dienes that contain a tertiary carbon stereogenic site and are promoted by 1.0-5.0 mol % of a copper complex of an N-heterocyclic carbene (NHC).(More)
Operational weather forecasting depends critically on the Geostationary Operational Environmental Satellite (GOES) system. The GOES constellation consists of an eastern satellite stationed at 75°W longitude, a western satellite stationed at 135°W longitude, plus in-orbit spares. As of mid2005, GOES-12 occupied the eastern slot, GOES-10 occupied the western(More)
The synthesis of a range of caged TRPV1 agonists and antagonists is reported. The photolysis characteristics of these compounds, when irradiated with a 355 nm laser, have been studied and in all cases the desired compound was produced. Photolysis of a caged TRPV1 agonist in cultured trigeminal neurons produced responses that were consistent with the(More)
When charged current weak interations are excluded, the neutral current weak interaction is formally similar to ordinary electromagnetism with a massive photon. In this spirit, the Maxwell equations for the fields of the Z-boson are derived from the standard model. These describe the Z-boson scalar and vector potentials, and the Z-boson electric and(More)
Aspercyclide A (1) is a biaryl ether containing 11-membered macrocyclic natural product antagonist of the human IgE-FcεRI protein-protein interaction (PPI); a key interaction in the signal transduction pathway for allergic disorders such as asthma. Herein we report a novel approach to the synthesis of the C19 methyl ether of aspercyclide A, employing a(More)