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Mutations at the mouse Fused locus have pleiotropic developmental effects, including the formation of axial duplications in homozygous embryos. The product of the Fused locus, Axin, displays similarities to RGS (Regulators of G-Protein Signaling) and Dishevelled proteins. Mutant Fused alleles that cause axial duplications disrupt the major mRNA, suggesting(More)
Hypoxia-inducible factors (HIFs), in particular HIF-1alpha, have been implicated in tumor biology. However, HIF target genes in the esophageal tumor microenvironment remain elusive. Gene expression profiling was performed upon hypoxia-exposed non-transformed immortalized human esophageal epithelial cells, EPC2-hTERT, and comparing with a gene signature of(More)
Hepatocyte growth factor (HGF) elicits a broad spectrum of biological activities, including epithelial cell dedifferentiation. One of the most widely used and best-studied polarized epithelial cell lines is the Madin-Darby canine kidney (MDCK) cell line. Here, we describe and validate the early response of polarized monolayers of MDCK cells stimulated with(More)
With advances in technology, mobile handheld devices-such as PDAs-have become very popular. In many real-life situations, users want to find structuring information using these mobile devices, which are convenient to use but have relatively limited resources. In this paper, we present a top-k structured mobile Web search engine. It uses a top-k adaptable(More)
How to measure similarity or distance for multiple categorical data? It is an important step for Data Mining and Knowledge Management process to measure similarity or distance between objects appropriately. Measurements for continuous data have been well-defined and relatively easy to be calculated. However, the notion of similarity for categorical data is(More)
The purpose of this study is to propose a classification scheme of Web communication. Because it is the most widely used platform of the Internet communication, the Web creates emerging global databases or information systems. Web communication structure is investigated as differentiated elements that can be recognized in the patterned communication flows(More)
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