James Jacobson

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Supported by the Office of International Affairs, National Cancer Institute (NCI), the "US-Japan Workshop on Immunological Biomarkers in Oncology" was held in March 2009. The workshop was related to a task force launched by the International Society for the Biological Therapy of Cancer (iSBTc) and the United States Food and Drug Administration (FDA) to(More)
Rapid automatic naming tasks are clinical tools for probing brain functions that underlie normal cognition. To compare performance for various stimuli in normal subjects and assess the effect of aging, we administered six single-dimension stimuli (color, form, number, letter, animal, and object) and five dual-dimension stimuli (color-form, color-number,(More)
A Quick Test of Cognitive Speed color, form, and color-form naming were administered to 300 normal participants (ages 15-95 years) to explore the effects of age on perceptual (single-dimension naming) and cognitive speed (dual-dimension naming). Naming time means (sec.) were consistent with previous findings. Correlations between age and naming time were(More)
To determine if direction of response affects reaction time, we measured the time for hand response to a visual stimulus, using a sensitive, microprocessor-based testing device to determine simple reaction time (RT), choice RT, and decision time. Mean simple RT was 207 +/- 3.7 msec. (mean +/- SEM); mean choice RT was 268 +/- 4.2 msec; and mean decision time(More)
Cocaine, a commonly used drug among HIV-1 positive individuals , has been demonstrated to increase HIV-1 replication in permissive cells and humanized mouse. The goal of this study is to examine the effects of cocaine on HIV-1 integration-a critical step in HIV-1 life cycle. Our data demonstrates that cocaine treatment enhances HIV-1 integration in primary(More)
Optical microscopy is a well-established technique that has wide ranging applications for imaging molecular dynamics of biological systems. Typically, these applications rely on external temperature controllers to maintain or change reactions rates of these biological systems. With increasing interest in applying low power microwaves to drive biological and(More)
Psychiatric factors play a major role in the AIDS pandemic. They have an impact on transmission, morbidity, coping, adherence, and quality of life and of death. Substance-related disorders are associated with HIV transmission through needle sharing, sexual transmission, exchange of sex for drugs, and perinatal transmission. Persons with AIDS have a high(More)
This article examines one aspect of the potential usefulness of critical items to the: Minnesota Multiphasic Personality Inventory -Adolescent (MMPI-A). Endorsement frequency data are presented on the Koss-Butcher (1973) and the Lachar-Wrobeli (1979) critical items for Minnesota Multiphasic Personality Inventory-2 (MMPI-2) adult normative and clinical(More)